Glutathione S-Transferase mu 1/GSTM1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-33523

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Mouse

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Glutathione S-Transferase mu 1/GSTM1 Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human Glutathione S-Transferase mu 1/GSTM1. The exact sequence is proprietary.

Reactivity Notes

Bovine (83%).

Localization

Cytoplasm

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

26 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Glutathione S-Transferase mu 1/GSTM1 Antibody

Western Blot: Glutathione S-Transferase mu 1/GSTM1 Antibody [NBP1-33523]

Western Blot: Glutathione S-Transferase mu 1/GSTM1 Antibody [NBP1-33523]

Western Blot: Glutathione S-Transferase mu 1/GSTM1 Antibody [NBP1-33523] - Human tissue extract (30 ug) was separated by 12% SDS-PAGE, and the membrane was blotted with GSTM1 antibody diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.
Immunohistochemistry-Paraffin: Glutathione S-Transferase mu 1/GSTM1 Antibody [NBP1-33523]

Immunohistochemistry-Paraffin: Glutathione S-Transferase mu 1/GSTM1 Antibody [NBP1-33523]

Immunohistochemistry-Paraffin: Glutathione S-Transferase mu 1/GSTM1 Antibody [NBP1-33523] - Rat heart GSTM1 antibody diluted at 1:400. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
Western Blot: Glutathione S-Transferase mu 1/GSTM1 Antibody [NBP1-33523]

Western Blot: Glutathione S-Transferase mu 1/GSTM1 Antibody [NBP1-33523]

Western Blot: Glutathione S-Transferase mu 1/GSTM1 Antibody [NBP1-33523] - A. 50 ug mouse brain lysate/extract 12% SDS-PAGE GSTM1 antibody dilution: 1:1000 The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.
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Applications for Glutathione S-Transferase mu 1/GSTM1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris-Glycine (pH7), 10% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Glutathione S-Transferase mu 1/GSTM1

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene.

Alternate Names

Glutathione STransferase mu 1, GST1, GSTM1, GTH4, GTM1

Gene Symbol

GSTM1

Additional Glutathione S-Transferase mu 1/GSTM1 Products

Product Documents for Glutathione S-Transferase mu 1/GSTM1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Glutathione S-Transferase mu 1/GSTM1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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