GMDS Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-83357

Novus Biologicals, part of Bio-Techne
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NBP1-83357
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (99%), Rat (99%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all GMDS Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: LAEYTADVDGVGTLRLLDAVKTCGLINSVKFYQASTSELYGKVQEIPQKETTPFYPRSPYGAAKLYAYWIVVNFREAYNLFAVNGILFNHESPRRGAN

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for GMDS Antibody

Immunohistochemistry-Paraffin: GMDS Antibody [NBP1-83357]

Immunohistochemistry-Paraffin: GMDS Antibody [NBP1-83357]

Immunohistochemistry-Paraffin: GMDS Antibody [NBP1-83357] - Staining in human duodenum and skeletal muscle tissues using anti-GMDS antibody. Corresponding GMDS RNA-seq data are presented for the same tissues.
Western Blot: GMDS Antibody [NBP1-83357]

Western Blot: GMDS Antibody [NBP1-83357]

Western Blot: GMDS Antibody [NBP1-83357] - Analysis in control (vector only transfected HEK293T lysate) and GMDS over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
Immunohistochemistry-Paraffin: GMDS Antibody [NBP1-83357]

Immunohistochemistry-Paraffin: GMDS Antibody [NBP1-83357]

Immunohistochemistry-Paraffin: GMDS Antibody [NBP1-83357] - Staining of human duodenum shows high expression.
View 1 more images

Applications for GMDS Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50

Western Blot

0.04-0.4 ug/ml
Application Notes
IHC-P, HIER pH6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GMDS

GDP-mannose 4,6-dehydratase (GMD; EC 4.2.1.47) catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose,the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third stepsof the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3,5-epimerase, 4-reductase, designated FX inhumans (MIM 137020).(supplied by OMIM)

Alternate Names

EC 4.2.1.47, GDP-D-mannose dehydratase, GDP-mannose 4,6-dehydratase, GMDGDP-mannose 4,6 dehydratase, SDR3E1, short chain dehydrogenase/reductase family 3E, member 1

Gene Symbol

GMDS

Additional GMDS Products

Product Documents for GMDS Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for GMDS Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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