GNIP Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-89751

Novus Biologicals, part of Bio-Techne
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NBP1-89751
NBP1-89751-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

IF/IHC, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all GNIP Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: LRVLKKELEDCEVFRSTEKKESKELLKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGVEITQLSKLSSQI

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (86%), Rat (83%). Human reactivity reported in scientific literature (PMID: 25851810).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for GNIP Antibody

Western Blot: GNIP Antibody [NBP1-89751]

Western Blot: GNIP Antibody [NBP1-89751]

Western Blot: GNIP Antibody [NBP1-89751] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp. Lane 4: Human plasma (IgG/HSA depleted). Lane 5: Human liver tissue. Lane 6: Human tonsil tissue
Immunocytochemistry/ Immunofluorescence: GNIP Antibody [NBP1-89751]

Immunocytochemistry/ Immunofluorescence: GNIP Antibody [NBP1-89751]

Immunocytochemistry/Immunofluorescence: GNIP Antibody [NBP1-89751] - Staining of human cell line U-2 OS shows localization to nucleoplasm, cytosol & vesicles. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: GNIP Antibody [NBP1-89751]

Immunohistochemistry-Paraffin: GNIP Antibody [NBP1-89751]

Immunohistochemistry-Paraffin: GNIP Antibody [NBP1-89751] - Staining of human skin shows strong cytoplasmic positivity in squamous epithelial cells.
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Applications for GNIP Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GNIP

GNIP is encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1, a B-box type 2, and a coiled-coil region. The protein localizes to both the nucleus and the cytoplasm, and may represent a participant in the initiation of glycogen synthesis. Multiple transcript variants have been found for this gene, and some of them encode the same isoform.

Alternate Names

Glycogenin-interacting protein, GNIPRING finger protein 90, RNF90tripartite motif protein TRIM7, tripartite motif containing 7, tripartite motif-containing 7, tripartite motif-containing protein 7

Gene Symbol

TRIM7

Additional GNIP Products

Product Documents for GNIP Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for GNIP Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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