GnRHR Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NLS209

Novus Biologicals, part of Bio-Techne
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NLS209
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (90%), Canine (95%), Equine (90%), Monkey (95%), Primate (95%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

View all GnRHR Antibodies »

Product Specifications

Immunogen

Synthetic 20 amino acid peptide from 3rd cytoplasmic domain of human GnRHR.

Epitope

3rd cytoplasmic domain

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gibbon (100%), Gorilla (95%), Marmoset (90%), Mouse (85%), Rat (85%), Sheep (85%), Bat (85%), Rabbit (85%), Opossum (85%), Hamster (80%), Guinea Pig (80%).

Localization

Secreted

Specificity

Human GNRHR. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for GnRHR Antibody - BSA Free

Immunohistochemistry-Paraffin: GnRHR Antibody - BSA Free [NLS209]

Immunohistochemistry-Paraffin: GnRHR Antibody - BSA Free [NLS209]

Immunohistochemistry-Paraffin: GnRHR Antibody [NLS209] - Analysis of anti-GNRHR antibody with human pituitary at 1 ug/ ml.
GnRHR Antibody - BSA Free

Immunohistochemistry-Paraffin: GnRHR Antibody - BSA Free [NLS209] -

Immunohistochemistry-Paraffin: GnRHR Antibody - BSA Free [NLS209] - Immunohistochemistry of formalin-fixed, paraffin-embedded Human Pituitary tissue

Applications for GnRHR Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:3000
Application Notes
.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: GnRHR

GnRHR is a Releasing-Hormone Receptor activated by gonadotropin-releasing hormone (GnRH). This receptor plays a major role in the regulation of reproductive functions. It modulates the synthesis and secretion of gonadotropin hormones such as luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary. In turn, LH and FSH regulate the release of steroid hormones from the gonads. Mutations in GnRHR have been linked to hypogonadotropic hypogonadism, a condition characterized by absence or delayed puberty and retarded bone maturation. GnRHR has been reported to be expressed mostly in the pituitary gonadotropes and in reproductive organs, including ovary, placenta, prostate, testis, and uterus. It is also expressed in breast, heart, kidney, liver, skeletal muscle, and thymus. No human ESTs have been isolated for this receptor.

Long Name

Gonadotropin-releasing Hormone Receptor

Alternate Names

GNRHR1, GRHR, HH7, LHRHR, LRHR, Luliberin

Entrez Gene IDs

2798 (Human)

Gene Symbol

GNRHR

Additional GnRHR Products

Product Documents for GnRHR Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for GnRHR Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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