Key Product Details

Species Reactivity

Validated:

Mouse

Applications

CyTOF-ready, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, In vivo assay

Label

Unconjugated

Antibody Source

Monoclonal Rat IgG2 Clone # AP-MAB0866

Format

Azide and BSA Free

Concentration

1.0 mg/ml

View all Ly-6G/Ly-6C (Gr-1) Antibodies »

Product Summary for Gr-1/Ly-6G Antibody (AP-MAB0866) - Azide and BSA Free

Immunogen

Mouse spontaneous T lymphoma line TK1

Clonality

Monoclonal

Host

Rat

Isotype

IgG2

Applications for Gr-1/Ly-6G Antibody (AP-MAB0866) - Azide and BSA Free

Application
Recommended Usage

Flow Cytometry

1:10-1:1000

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Immunoprecipitation

1:10-1:500
Application Notes
In vivo depletion of PMN and Myeloid suppressor cells. Endotoxin level: Extremely low level of LPS (< 0.002EU/ug IgG) This antibody may also be useful in IHC-frozen. This antibody is CyTOF ready.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Ly-6G/Ly-6C (Gr-1)

Gr-1 is a 21-25 kD protein also known as Ly-6G/Ly-6C. This myeloid differentiation antigen is a glycosylphosphatidylinositol (GPI)-linked protein expressed on granulocytes and macrophages. In bone marrow, the expression levels of Gr-1 directly correlate with granulocyte differentiation and maturation; Gr-1 is also transiently expressed on bone marrow cells in the monocyte lineage. Gr-1+ cells have recently been implicated in the development of antitumor responses.

Long Name

A Myeloid Differentiation Antigen

Alternate Names

Ly-6C, Ly-6G, Ly6G

Entrez Gene IDs

546644 (Mouse)

Gene Symbol

LY6G

Additional Ly-6G/Ly-6C (Gr-1) Products

Product Documents for Gr-1/Ly-6G Antibody (AP-MAB0866) - Azide and BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Gr-1/Ly-6G Antibody (AP-MAB0866) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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