GRB10 Antibody (1A7)

Novus Biologicals, part of Bio-Techne | Catalog # H00002887-M01

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 1A7

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all GRB10 Antibodies »

Product Specifications

Immunogen

GRB10 (AAH24285, 61 a.a. ~ 150 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. AVRRLQEEDQQFRTSSLPAIPNPFPELCGPGSPPVLTPGSLPPSQAAAKQDVKVFSEDGTSKVVEILADMTARDLCQLLVYKSHCVDDNS

Specificity

GRB10 - growth factor receptor-bound protein 10

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for GRB10 Antibody (1A7)

Western Blot: GRB10 Antibody (1A7) [H00002887-M01]

Western Blot: GRB10 Antibody (1A7) [H00002887-M01]

Western Blot: GRB10 Antibody (1A7) [H00002887-M01] - GRB10 monoclonal antibody (M01), clone 1A7. Analysis of GRB10 expression in IMR-32.
Sandwich ELISA: GRB10 Antibody (1A7) [H00002887-M01] - Detection limit for recombinant GST tagged GRB10 is approximately 0.03ng/ml as a capture antibody.

Applications for GRB10 Antibody (1A7)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: GRB10

The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner. Alternatively spliced transcript variants encoding different isoforms have been identified.

Alternate Names

Grb-10, GRB10 adapter protein, GRB10 adaptor protein, GRBIR, GRB-IR, growth factor receptor-bound protein 10, Insulin receptor-binding protein Grb-IR, IRBP, KIAA0207, maternally expressed gene 1, MEG1, RSS

Entrez Gene IDs

2887 (Human)

Gene Symbol

GRB10

OMIM

601523 (Human)

UniProt

AAH24285 (Human)

Additional GRB10 Products

Product Documents for GRB10 Antibody (1A7)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for GRB10 Antibody (1A7)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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