GRB2 Antibody (SAIC-19D-1F4) - Chimeric - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-09000

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-09000-0.025mg
NBP3-09000-0.2mg
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Mass Spectrometry, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Mouse IgG1 kappa Clone # SAIC-19D-1F4

Format

Azide and BSA Free

Concentration

1 mg/ml

View all GRB2 Antibodies »

Product Summary for GRB2 Antibody (SAIC-19D-1F4) - Chimeric - Azide and BSA Free

Immunogen

Peptide "FGNDVQHFK", derived from the Growth factor receptor-bound protein 2, conjugated to KLH.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Applications for GRB2 Antibody (SAIC-19D-1F4) - Chimeric - Azide and BSA Free

Application
Recommended Usage

Mass Spectrometry

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
This is a chimeric antibody created for improved compatibility with existing reagents, assays and techniques.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Format

Azide and BSA Free

Preservative

0.02% Proclin 300

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GRB2

The growth factor bound protein 2 (GRB2) is a 25 kDa cytosolic protein that contains one src homology (SH2) domain and two SH3 domains (1). GRB2 associates with Tyrosine phosphorylated EGFRs and PDGFRs via its SH2 domain. GRB2 also plays a crucial role in two separate insulin pathways leading from the insulin receptor to the Ras protein thus affecting mitogenic signaling (2). Additionally GBR2, a bifunctional adaptor protein, recruits Sos for Ras activation and subsequent signal transmission (3).

Long Name

Growth Factor Receptor-Bound Protein 2

Alternate Names

ASH, EGFRBP-GRB2, Grb3-3

Gene Symbol

GRB2

Additional GRB2 Products

Product Documents for GRB2 Antibody (SAIC-19D-1F4) - Chimeric - Azide and BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for GRB2 Antibody (SAIC-19D-1F4) - Chimeric - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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