Gremlin 1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-56883

Novus Biologicals, part of Bio-Techne
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NB100-56883
NB100-56883SS
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Predicted:

Mouse (94%), Rat (94%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin

Cited:

IF/IHC, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all Gremlin Antibodies »

Product Specifications

Immunogen

A synthetic peptide containing amino acids QPGSRNRGRGQGRGTA (52-67) of human CKTSF1B1 (NM_013372).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Gremlin 1 Antibody

Immunohistochemistry-Paraffin: Gremlin 1 Antibody [NB100-56883]

Immunohistochemistry-Paraffin: Gremlin 1 Antibody [NB100-56883]

Immunohistochemistry-Paraffin: Gremlin 1 Antibody [NB100-56883] - Detection of Gremlin in human colon cancer tissue using antibody at 5 ug/ml.

Applications for Gremlin 1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:20-1:1000

Immunohistochemistry-Frozen

reported in scientific literature (Namkoong et al (2006))

Immunohistochemistry-Paraffin

2.5-10 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Gremlin

In Xenopus, Gremlin belongs to a novel gene family that act as BMP antagonists in embryonic explants. The human homolog of Drm/Gremlin (CKTFS1B1) is localized on human chromosome 15q13--> q15. DRM-specific mRNA is expressed in different human tissues, including brain, ovary, intestine and colon. It has been suggested that down-regulation of DRM is associated with tumor progression, and support the hypothesis that human DRM may play an important role during both neuroembryological development and carcinogenesis.

Alternate Names

DAND2, DRM, GREM1

Entrez Gene IDs

26585 (Human)

Gene Symbol

GREM1

UniProt

O60565

Additional Gremlin Products

Product Documents for Gremlin 1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Gremlin 1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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