GRIM19 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-56621

Novus Biologicals, part of Bio-Techne
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NB100-56621
NB100-56621SS
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

View all GRIM19 Antibodies »

Product Specifications

Immunogen

This antibody was developed by immunizing rabbits with a mixture of synthetic peptides of human GRIM-19.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for GRIM19 Antibody

Western Blot: GRIM19 Antibody [NB100-56621]

Western Blot: GRIM19 Antibody [NB100-56621]

Western Blot: GRIM19 Antibody [NB100-56621] - Analysis of GRIM-19 in A) human heart and B) HeLa cell lysate using GRIM-19 antibody at 1:500. Goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.
Immunohistochemistry-Paraffin: GRIM19 Antibody [NB100-56621]

Immunohistochemistry-Paraffin: GRIM19 Antibody [NB100-56621]

Immunohistochemistry-Paraffin: GRIM19 Antibody [NB100-56621] - Analysis of human liver using GRIM-19 antibody at 1:100.

Applications for GRIM19 Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:100

Western Blot

1:100 - 1:1000
Application Notes
In HeLa, an approx. 16 kDa band is observed

Formulation, Preparation, and Storage

Purification

Unpurified

Formulation

Whole antisera with PBS and 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GRIM19

Mitochondrial NADH:ubiquinone oxidoreductase (complex I) catalyzes the first step in the electron transport chain, the oxidation of NADH to NAD+ coupled to proton translocation across the inner mitochondrial membrane. GRIM-19 is a component of the complex I and is a product of a cell death regulatiry gene induced by interferon-b and retinoic acid. GRIM-19 has previously been detected in HeLa cells, predominantly in the nucleus, though punctate staining of the cytoplasm was also observed.

Alternate Names

B16.6, CDA016, Cell death regulatory protein GRIM-19, cell death-regulatory protein GRIM19, CI-B16.6, complex I B16.6 subunit, Complex I-B16.6, FLJ58045, FLJ59191, Gene associated with retinoic and IFN-induced mortality 19 protein, Gene associated with retinoic and interferon-induced mortality 19 protein, GRIM-19CGI-39, GRIM19NADH-ubiquinone oxidoreductase B16.6 subunit, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13, NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13

Entrez Gene IDs

51079 (Human)

Gene Symbol

NDUFA13

UniProt

Q9P0J0 (Human)

Additional GRIM19 Products

Product Documents for GRIM19 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for GRIM19 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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