GRIP1 Antibody (4A9)

Novus Biologicals, part of Bio-Techne | Catalog # H00023426-M05-100ug

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 4A9

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all GRIP1 Antibodies »

Product Specifications

Immunogen

GRIP1 (XP_290559, 851 a.a. ~ 950 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. QSGILRELEATIMSGSTMSLNHEAPTPRSQLGRQASFQERSSSRPHYSQTTRSNTLPSDVGRKSVTLRKMKQEIKEIMSPTPVELHKVTLYKDSDMEDFG

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Scientific Data Images for GRIP1 Antibody (4A9)

Western Blot: GRIP1 Antibody (4A9) [H00023426-M05-100ug]

Western Blot: GRIP1 Antibody (4A9) [H00023426-M05-100ug]

Western Blot: GRIP1 Antibody (4A9) [H00023426-M05-100ug] - Detection against Immunogen (36.74 KDa)
Western Blot: GRIP1 Antibody (4A9) [H00023426-M05-100ug]

Western Blot: GRIP1 Antibody (4A9) [H00023426-M05-100ug]

Western Blot: GRIP1 Antibody (4A9) [H00023426-M05-100ug] - Monoclonal antibody (M05), clone 4A9. Western Blot analysis of GRIP1 expression in K-562.
ELISA: GRIP1 Antibody (4A9) [H00023426-M05-100ug]

ELISA: GRIP1 Antibody (4A9) [H00023426-M05-100ug]

ELISA: GRIP1 Antibody (4A9) [H00023426-M05-100ug] - Detection limit for recombinant GST tagged GRIP1 is 0.1 ng/ml as a capture antibody.

Applications for GRIP1 Antibody (4A9)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: GRIP1

Steroid and thyroid hormones and retinoic acid regulate a complex array of gene expression activity via intracellular receptor transcription factors belonging to the ligand-dependent nuclear receptor superfamily. Adding to the complexity of function of these transcription factors are associated proteins known as coactivators and corepressors which, as their names suggest, enhance or depress transcription activity of the nuclear receptor with which they associate. Glucocorticoid receptor interacting protein-1 (GRIP 1), or Transcription Intermediary Factor 2 (TIF 2), is a member of a family of transcriptional coactivator proteins which includes steroid receptor coactivator-1 (SRC 1) and Amplified in breast cancer-1 (AIB 1).GRIP1 has been shown to interact and stimulate transcriptional activity of the retinoic acid, retinoid X, vitamin D, mineralocorticoid, glucocorticoid, thyroid hormone, androgen, estrogen, progesterone, and peroxisome proliferator activated receptors. GRIP 1 also contains several copies of the conserved LXXLL/LLXXL motif which has been demonstrated to be critical to receptor-coactivator interactions.

Alternate Names

glutamate receptor interacting protein 1, glutamate receptor-interacting protein 1, GRIP, GRIP-1

Entrez Gene IDs

23426 (Human)

Gene Symbol

GRIP1

OMIM

604597 (Human)

UniProt

XP_290559 (Human)

Additional GRIP1 Products

Product Documents for GRIP1 Antibody (4A9)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for GRIP1 Antibody (4A9)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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