GRIP1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NB120-2842

Novus Biologicals, part of Bio-Techne
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NB120-2842
NB120-2842-0.025mg
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Key Product Details

Species Reactivity

Human, Hamster

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all GRIP1 Antibodies »

Product Specifications

Immunogen

Synthetic peptide corresponding to residues P(206) L P D S E E E G H D S(217) C of human GRIP1.

Reactivity Notes

Cross-reactivity with Hamster.

Localization

Nuclear

Specificity

GRIP1

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for GRIP1 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: GRIP1 Antibody - BSA Free [NB120-2842]

Immunocytochemistry/ Immunofluorescence: GRIP1 Antibody - BSA Free [NB120-2842]

Immunocytochemistry/Immunofluorescence: GRIP1 Antibody [NB120-2842] - Immunolocalization of GRIP1 in CHO cells.

Applications for GRIP1 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1 - 2 ug/ml
Application Notes
Successful WB usage.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: GRIP1

Steroid and thyroid hormones and retinoic acid regulate a complex array of gene expression activity via intracellular receptor transcription factors belonging to the ligand-dependent nuclear receptor superfamily. Adding to the complexity of function of these transcription factors are associated proteins known as coactivators and corepressors which, as their names suggest, enhance or depress transcription activity of the nuclear receptor with which they associate. Glucocorticoid receptor interacting protein-1 (GRIP 1), or Transcription Intermediary Factor 2 (TIF 2), is a member of a family of transcriptional coactivator proteins which includes steroid receptor coactivator-1 (SRC 1) and Amplified in breast cancer-1 (AIB 1).GRIP1 has been shown to interact and stimulate transcriptional activity of the retinoic acid, retinoid X, vitamin D, mineralocorticoid, glucocorticoid, thyroid hormone, androgen, estrogen, progesterone, and peroxisome proliferator activated receptors. GRIP 1 also contains several copies of the conserved LXXLL/LLXXL motif which has been demonstrated to be critical to receptor-coactivator interactions.

Alternate Names

glutamate receptor interacting protein 1, glutamate receptor-interacting protein 1, GRIP, GRIP-1

Entrez Gene IDs

23426 (Human)

Gene Symbol

GRIP1

Additional GRIP1 Products

Product Documents for GRIP1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for GRIP1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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