GRP78/HSPA5 Antibody [DyLight 550]

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-06277R

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Alexa Fluor 350

NBP1-06277AF350

Alexa Fluor 405

NBP1-06277AF405

Alexa Fluor 488

NBP1-06277AF488

Alexa Fluor 532

NBP1-06277AF532

Alexa Fluor 594

NBP1-06277AF594

Alexa Fluor 647

NBP1-06277AF647

Alexa Fluor 700

NBP1-06277AF700

Alexa Fluor 750

NBP1-06277AF750

Allophycocyanin

NBP1-06277APC

Biotin

NBP1-06277B

CoraFluor 1

NBP1-06277CL1

DyLight 350

NBP1-06277UV

DyLight 405

NBP1-06277V

DyLight 488

NBP1-06277G

DyLight 594

NBP1-06277DL594

DyLight 650

NBP1-06277C

DyLight 680

NBP1-06277FR

DyLight 755

NBP1-06277IR

FITC

NBP1-06277F

HRP

NBP1-06277H

Janelia Fluor 525

NBP1-06277JF525

Janelia Fluor 549

NBP1-06277JF549

Janelia Fluor 646

NBP1-06277JF646

Janelia Fluor 669

NBP1-06277JF669

mFluor Violet 450 SE

NBP1-06277MFV450

mFluor Violet 500 SE

NBP1-06277MFV500

mFluor Violet 610 SE

NBP1-06277MFV610

PE

NBP1-06277PE

PerCP

NBP1-06277PCP

Forumulation

Catalog #

BSA Free

NBP1-06277

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Predicted:

Golden Syrian Hamster (100%), Primate (92%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Simple Western, Western Blot

Label

DyLight 550 (Excitation = 562 nm, Emission = 576 nm)

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all GRP78/HSPA5 Antibodies »

Product Specifications

Immunogen

Synthetic peptide made to a C-terminal portion of rat GRP78 (within residues 600-654). [Swiss-Prot# P06761]

Localization

Endoplasmic reticulum lumen. Melanosome. Note= Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Marker

ER Stress Marker

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for GRP78/HSPA5 Antibody [DyLight 550]

Application

Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Simple Western

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: GRP78/HSPA5

GRP78 (HSPA5), also referred to as 'immunoglobulin heavy chain-binding protein' (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER). Because so many ER proteins interact transiently with GRP78, it may play a key role in monitoring protein transport through the cell. BiP is also overexpressed in many cancers and has been hypothesized to actively regulate multiple malignant phenotypes including cell growth, migration, and invasion.

Long Name

75 KD Glucose Regulated Protein

Alternate Names

BIP, HSP70-5, HSPA5

Gene Symbol

HSPA5

Additional GRP78/HSPA5 Products

Product Documents for GRP78/HSPA5 Antibody [DyLight 550]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for GRP78/HSPA5 Antibody [DyLight 550]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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