GTF2H2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-56841

Novus Biologicals, part of Bio-Techne
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NBP2-56841
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (97%), Rat (96%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all GTF2H2 Antibodies »

Product Summary for GTF2H2 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: HVSPPPASSSSECSLIRMGFPQHTIASLSDQDAKPSFSMAHLDGNTEPGLTLGGYFCPQCRAKYCELPVECKICG

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for GTF2H2 Antibody

Western Blot: GTF2H2 Antibody [NBP2-56841]

Western Blot: GTF2H2 Antibody [NBP2-56841]

Western Blot: GTF2H2 Antibody [NBP2-56841] - Analysis in human cell line RT-4.
Immunocytochemistry/ Immunofluorescence: GTF2H2 Antibody [NBP2-56841]

Immunocytochemistry/ Immunofluorescence: GTF2H2 Antibody [NBP2-56841]

Immunocytochemistry/Immunofluorescence: GTF2H2 Antibody [NBP2-56841] - Staining of human cell line U-251 MG shows localization to nuclear speckles. Antibody staining is shown in green.

Applications for GTF2H2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Western Blot

0.04-0.4 ug/ml
Application Notes
ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GTF2H2

Initiation of transcription from protein-coding genes in eukaryotes is a complex process that requires RNA polymerase II, as well as families of basal transcription factors. Binding of the factor TFIID (TBP) to the TATA box is believed to be the first step in the formation of a multiprotein complex containing several additional factors, including TFIIA, TFIIB, TFIIE, TFIIF and TFII. TFIIH (or BTF2) is a multisubunit transcription/DNA repair factor that possesses several enzymatic activities. The core of TFIIH is composed of five subunits, designated p89 (XPB or ERCC3), p62, p52, p44 and p34. Additional subunits of the TFIIH complex are p80 (XPD or ERCC2) and the ternary kinase complex composed of Cdk7, cyclin H and MAT1. Both p89 and p80 have ATP-dependent helicase activity. The p62, p52 and p44 subunits have been shown to be involved in nucleotide excision repair.

Alternate Names

Basic transcription factor 2 44 kDa subunit, BTF2, BTF2 p44, BTF2P44TFIIH basal transcription factor complex p44 subunit, General transcription factor IIH polypeptide 2, general transcription factor IIH subunit 2, general transcription factor IIH, polypeptide 2 (44kD subunit), general transcription factor IIH, polypeptide 2, 44kD subunit, general transcription factor IIH, polypeptide 2, 44kDa, MGC102806, T-BTF2P44, TFIIH

Gene Symbol

GTF2H2

Additional GTF2H2 Products

Product Documents for GTF2H2 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for GTF2H2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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