Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all GTF3C4 Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 625 and 675 of human general transcription factor 3C polypeptide 4 (Transcription factor IIIC 90 kDa subunit) using the numbering given in entry NP_036336.1 (GeneID 9329).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for GTF3C4 Antibody

Immunohistochemistry: GTF3C4 Antibody [NB100-60434]

Immunohistochemistry: GTF3C4 Antibody [NB100-60434]

Immunohistochemistry: GTF3C4 Antibody [NB100-60434] - Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti- GTF3C4/TFIIIC90 used at a dilution of 1:5,000 (0.2ug/ml). Detection: DAB
Immunoprecipitation: GTF3C4 Antibody [NB100-60434]

Immunoprecipitation: GTF3C4 Antibody [NB100-60434]

Immunoprecipitation: GTF3C4 Antibody [NB100-60434] - Detection of Human GTF3C4/TFIIIC90 on HeLa whole cell lysate using NB100-60434. GTF3C4/TFIIIC90 was also IPed by rabbit anti-GTF3C4/TFIIIC90 antibodies NB100-60432 and NB100-60433.

Applications for GTF3C4 Antibody

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Immunoprecipitation

1:10-1:500
Application Notes
This antibody is not recommended for Western Blot analysis.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: GTF3C4

General transcription factor 3C polypeptide 4 (GTF3C4/TFIIIC90) is a subunit of the TFIIIC DNA-binding factor required for transcription of tRNA and 5S rRNA genes by RNA polymerase III. Human TFIIIC is composed of six subunits: TFIIIC220, TFIIIC110, TFIIIC102, TFIIIC90 and TFIIIC63, and TFIIIC35. GTF3C4/TFIIIC90 is required for RNA polymerase III transcription and interacts with TFIIIC220, TFIIIC110, TFCIIIC63, TFIIIB90, and RPC39. GTF3C4/TFIIIC90 has been shown to possess acetyltransferase activity specific for histone H3. Alternate names for GTF3C4/TFIIIC90 include transcription factor IIIC subunit delta, TF3C-delta, TFIIIC 90 kDa subunit, FLJ21002, and MGC138450.

Alternate Names

EC 2.3.1.48, FLJ21002, general transcription factor 3C 4, general transcription factor 3C polypeptide 4, general transcription factor IIIC, polypeptide 4 (90kD), general transcription factor IIIC, polypeptide 4, 90kDa, KAT12, TF3C-delta, TFIII90, TFIIIC 90 kDa subunit, TFIIIC290, TFIIIC90MGC138450, TFIIICDELTA, Transcription factor IIIC 90 kDa subunit, Transcription factor IIIC subunit delta

Entrez Gene IDs

9329 (Human)

Gene Symbol

GTF3C4

UniProt

NP_036336.1 (Human)

Additional GTF3C4 Products

Product Documents for GTF3C4 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for GTF3C4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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