GUCY2D Antibody (4E12)

Novus Biologicals, part of Bio-Techne | Catalog # H00003000-M01

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 4E12

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all GUCY2D Antibodies »

Product Specifications

Immunogen

GUCY2D (NP_000171, 521 a.a. ~ 630 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. RKVAQGSRSSLGARSMSDIRSGPSQHLDSPNIGVYEGDRVWLKKFPGDQHIAIRPATKTAFSKLQELRHENVALYLGLFLARGAEGPAALWEGNLAVVSEHCTRGSLQDL

Specificity

GUCY2D - guanylate cyclase 2D, membrane (retina-specific)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for GUCY2D Antibody (4E12)

Western Blot: GUCY2D Antibody (4E12) [H00003000-M01]

Western Blot: GUCY2D Antibody (4E12) [H00003000-M01]

Western Blot: GUCY2D Antibody (4E12) [H00003000-M01] - GUCY2D monoclonal antibody (M01), clone 4E12. Analysis of GUCY2D expression in human spleen.
Sandwich ELISA: GUCY2D Antibody (4E12) [H00003000-M01] - Detection limit for recombinant GST tagged GUCY2D is approximately 0.1ng/ml as a capture antibody.

Applications for GUCY2D Antibody (4E12)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: GUCY2D

This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases. [provided by RefSeq]

Alternate Names

CORD6cone rod dystrophy 5/6, CYGD, EC 4.6.1, guanylate cyclase 2D, membrane (retina-specific), Guanylate cyclase 2D, retinal, GUC1A4, GUC2DCORD5, LCA, LCA1RCD2, retGC, RETGC1, RETGC-1EC 4.6.1.2, retinal guanylyl cyclase 1, Rod outer segment membrane guanylate cyclase, ROSGC, ROS-GC, ROS-GC1

Entrez Gene IDs

3000 (Human)

Gene Symbol

GUCY2D

OMIM

204000 (Human)

UniProt

NP_000171 (Human)

Additional GUCY2D Products

Product Documents for GUCY2D Antibody (4E12)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for GUCY2D Antibody (4E12)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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