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GULP1/CED-6 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-84553

Novus Biologicals, part of Bio-Techne
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NBP1-84553
NBP1-84553-25ul

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Human

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: KTDKRIFTFICKDSESNKHLCYVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGLQKRIQDLETENMELKNKVQDLENQLRITQVSA

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for GULP1/CED-6 Antibody

Immunohistochemistry-Paraffin: GULP1/CED-6 Antibody [NBP1-84553]

Immunohistochemistry-Paraffin: GULP1/CED-6 Antibody [NBP1-84553]

Immunohistochemistry-Paraffin: GULP1/CED-6 Antibody [NBP1-84553] - Staining in human smooth muscle and tonsil tissues using anti-GULP1 antibody. Corresponding GULP1 RNA-seq data are presented for the same tissues.
Western Blot: GULP1/CED-6 Antibody [NBP1-84553]

Western Blot: GULP1/CED-6 Antibody [NBP1-84553]

Western Blot: GULP1/CED-6 Antibody [NBP1-84553] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells). Lane 2: NBT-II cell lysate (Rat Wistar bladder tumor cells).
Immunocytochemistry/ Immunofluorescence: GULP1/CED-6 Antibody [NBP1-84553]

Immunocytochemistry/ Immunofluorescence: GULP1/CED-6 Antibody [NBP1-84553]

Immunocytochemistry/Immunofluorescence: GULP1/CED-6 Antibody [NBP1-84553] - Staining of human cell line U-2 OS shows localization to vesicles. Antibody staining is shown in green.

Applications for GULP1/CED-6 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GULP1/CED-6

The prompt clearance of cells undergoing apoptosis is critical during embryonic development, normal tissue turnover, as well as inflammation and autoimmunity. CED6 and its human homologue gulp, encode an adapter protein, whose function in engulfment. The upstream and downstream components of CED6 mediated signaling are not known. Recently, CED1 has been shown to encode a transmembrane protein on phagocytic cells, with two functional sequence motifs in its cytoplasmic tail that are important for engulfment.

Alternate Names

CED6

Gene Symbol

GULP1

Additional GULP1/CED-6 Products

Product Documents for GULP1/CED-6 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for GULP1/CED-6 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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