GW182 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-06657

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all GW182 Antibodies »

Product Specifications

Immunogen

Produced in rabbits immunized with a synthetic peptide corresponding to the C-terminus of the Human GW182.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for GW182 Antibody

Immunohistochemistry: GW182 Antibody [NBP3-06657]

Immunohistochemistry: GW182 Antibody [NBP3-06657]

Immunohistochemistry: GW182 Antibody [NBP3-06657] - Immunochemical staining of human TNRC6A in human breast carcinoma with NBP3-06657 (1:300, formalin-fixed paraffin embedded sections).

Applications for GW182 Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:200-1:500

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GW182

GW182 (glycine-tryptophan protein of 182 kDa) is a member of the trinucleotide repeat containing 6 protein family. It functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. GW182 has been found to associate with messenger RNAs and Argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies. Inhibition of GW182 expression delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing.

Alternate Names

CAG repeat protein 26, CAGH26FLJ22043, DKFZp666E117, EMSY interactor protein, Glycine-tryptophan protein of 182 kDa, GW182 autoantigen, GW182GW1, KIAA1460EDIE, MGC75384, Protein GW1, TNRC6, trinucleotide repeat containing 6, trinucleotide repeat containing 6A, trinucleotide repeat-containing gene 6A protein

Gene Symbol

TNRC6A

Additional GW182 Products

Product Documents for GW182 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for GW182 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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