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HAPLN2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-91977

Novus Biologicals, part of Bio-Techne
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NBP1-91977

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (94%), Rat (94%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: DPASHPGPHYLLPPIHEVIHSHRGATATLPCVLGTTPPSYKVRWSKVEPGELRETLILITNGLH

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for HAPLN2 Antibody

Western Blot: HAPLN2 Antibody [NBP1-91977]

Western Blot: HAPLN2 Antibody [NBP1-91977]

Western Blot: HAPLN2 Antibody [NBP1-91977] - Analysis in control (vector only transfected HEK293T lysate) and HAPLN2 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
Immunohistochemistry-Paraffin: HAPLN2 Antibody [NBP1-91977]

Immunohistochemistry-Paraffin: HAPLN2 Antibody [NBP1-91977]

Immunohistochemistry-Paraffin: HAPLN2 Antibody [NBP1-91977] - Staining in human cerebral cortex and kidney tissues using NBP1-91977 antibody. Corresponding HAPLN2 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: HAPLN2 Antibody [NBP1-91977]

Immunohistochemistry-Paraffin: HAPLN2 Antibody [NBP1-91977]

Immunohistochemistry-Paraffin: HAPLN2 Antibody [NBP1-91977] - Staining of human cerebral cortex shows weak positivity in neuropil.

Applications for HAPLN2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HAPLN2

The 340 amino acid long, 37 kDA hyaluronan and proteoglycan link protein 2 encoded by the HAPLN2 gene monitors binding of versication V2 to hyaluronic acid. This protein may be a participant in the formation of the hyaluronan-associated matrix in the central nervous system (CNS). This matrix encourages neuronal confuction and structural stabilization. HAPLN2 participates in PTEN pathway, MAPK signaling, UPA-UPAR pathway, and transendothelial migration of leukocytes. It has been researched regarding its role in rabies, schizophrenia, neuronitis, and malignant glioma.

Long Name

Hyaluronan And Proteoglycan Link Protein 2

Alternate Names

BRAL1

Gene Symbol

HAPLN2

Additional HAPLN2 Products

Product Documents for HAPLN2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for HAPLN2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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