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HCC1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-88200

Novus Biologicals, part of Bio-Techne
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NBP1-88200

Key Product Details

Validated by

Knockout/Knockdown

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Knockdown Validated, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: LAAAASVQPLATQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKNSAQGNVYVKCPSIAAAIAAVNALHGRWFAGKMITAAYVPLPTYHNLFPDSMTATQ

Reactivity Notes

Reactivity reported in scientific literature (PMID: 22711543)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for HCC1 Antibody

Knockdown Validated: HCC1 Antibody [NBP1-88200]

Knockdown Validated: HCC1 Antibody [NBP1-88200]

Knockdown Validated: HCC1 Antibody [NBP1-88200] - Analysis in Caco-2 cells transfected with control siRNA, target specific siRNA probe #1, using anti-RBM39 antibody. Remaining relative intensity is presented. Loading control: anti-GAPDH.
Immunohistochemistry-Paraffin: HCC1 Antibody [NBP1-88200]

Immunohistochemistry-Paraffin: HCC1 Antibody [NBP1-88200]

Immunohistochemistry-Paraffin: HCC1 Antibody [NBP1-88200] - Staining of human testis shows moderate to strong nuclear positivity in cells in seminiferous ducts.
Immunohistochemistry-Paraffin: HCC1 Antibody [NBP1-88200]

Immunohistochemistry-Paraffin: HCC1 Antibody [NBP1-88200]

Immunohistochemistry-Paraffin: HCC1 Antibody [NBP1-88200] - Staining of human cerebral cortex shows moderate to strong nuclear positivity in neurons.

Applications for HCC1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HCC1

HCC1 is encoded by this gene is an RNA binding protein and possible splicing factor. The encoded protein is found in the nucleus, where it colocalizes with core spliceosomal proteins. Studies of a mouse protein with high sequence similarity to this protein suggest that this protein may act as a transcriptional coactivator for JUN/AP-1 and estrogen receptors. Multiple transcript variants encoding different isoforms have been observed for this gene.

Long Name

RNA-binding protein 39

Alternate Names

CAPER alpha, CAPERalpha, RBM39, RNPC2

Gene Symbol

RBM39

Additional HCC1 Products

Product Documents for HCC1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for HCC1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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