HDAC6 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-78981

Novus Biologicals, part of Bio-Techne
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NBP1-78981SS
NBP1-78981
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Cited:

Mouse

Applications

Validated:

Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry (Negative), Western Blot (Negative)

Cited:

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.07 mg/ml

View all Histone Deacetylase 6/HDAC6 Antibodies »

Product Specifications

Immunogen

A synthetic peptide made to a C-terminal portion of the human HDAC6 protein (between residues 1175-1215). [UniProt Q9UBN7]

Localization

Nucleus. Cytoplasm. Note: It is cytoplasmic when associated with microtubules.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for HDAC6 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: HDAC6 Antibody - BSA Free [NBP1-78981]

Immunocytochemistry/ Immunofluorescence: HDAC6 Antibody - BSA Free [NBP1-78981]

Immunocytochemistry/Immunofluorescence: HDAC6 Antibody [NBP1-78981] - HDAC-6 antibody was tested in HeLa cells with FITC (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and DyLight 550 (red).
Flow Cytometry: HDAC6 Antibody - BSA Free [NBP1-78981]

Flow Cytometry: HDAC6 Antibody - BSA Free [NBP1-78981]

Flow Cytometry: HDAC6 Antibody [NBP1-78981] - Analysis using the Alexa Fluor (R) 488 conjugate of NBP1-78981. Staining of isolated T-cells. Image from verified customer review (Andressa Sodre, Moffitt Cancer Center).

Applications for HDAC6 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100
Application Notes
Antibody did not work in IHC-paraffin embedded sections in mouse intestine or Western blot.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS, 30% Glycerol

Format

BSA Free

Preservative

0.05% Sodium Azide

Concentration

1.07 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Histone Deacetylase 6/HDAC6

Histone deacetylase 6 (HDAC-6, HD6, and JM21) is a class II histone deacetylase/AcuC/AphA family member. HDAC-6 primarily functions to alter chromosome structure, regulate transcription factor access to DNA, and deacetylate the lysine residues on the N-terminal region of histones. The deacetylase activity, in turn, has a role in the degradation of misfolded proteins by autophagy (PMID: 21235576). The HDAC-6 protein contains two catalytic domains that function independently of each other and plays an important role in cell motility (microtubule dependent) by the deacetylation of tubulin. Research involving HDAC-6 includes cancer development and progression, Parkinson's disease, and epigenetics (PMID: 21455583, 21235576).

Long Name

Histone Deacetylase 6

Alternate Names

CPBHM, FLJ16239, HD6, HDAC6, JM21, PPP1R90

Entrez Gene IDs

10013 (Human)

Gene Symbol

HDAC6

UniProt

Q9UBN7 (Human)

Additional Histone Deacetylase 6/HDAC6 Products

Product Documents for HDAC6 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for HDAC6 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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