HDAC9 Antibody (S01-8I6)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-19871

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-19871-100ul
NBP3-19871-50ul
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Key Product Details

Species Reactivity

Validated:

Human, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S01-8I6

Concentration

0.3 mg/ml

View all HDAC9 Antibodies »

Product Summary for HDAC9 Antibody (S01-8I6)

Immunogen

A synthetic peptide of human HDAC9 (Uniprot # Q9UKV0)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

150 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for HDAC9 Antibody (S01-8I6)

Western Blot: HDAC9 Antibody (S01-8I6) [NBP3-19871]

Western Blot: HDAC9 Antibody (S01-8I6) [NBP3-19871]

Western Blot: HDAC9 Antibody (S01-8I6) [NBP3-19871] - Western blot detection of HDAC9 in A549, HL-60 cell lysates using NBP3-19871 (1:1000 diluted). Predicted band size: 111kDa. Observed band size: 150kDa.
Immunohistochemistry-Paraffin: HDAC9 Antibody (S01-8I6) [NBP3-19871]

Immunohistochemistry-Paraffin: HDAC9 Antibody (S01-8I6) [NBP3-19871]

Immunohistochemistry-Paraffin: HDAC9 Antibody (S01-8I6) [NBP3-19871] - Immunohistochemical of HDAC9 in Human tonsil tissue using NBP3-19871 at dilution 1/20

Applications for HDAC9 Antibody (S01-8I6)

Application
Recommended Usage

Immunohistochemistry

1/50

Western Blot

1/2000-1/10000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HDAC9

In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, PCAF (p300/CBP-associated factor), p300/CBP, HAT1 and the TFIID subunit TAF II p250. Mammalian HDAC8, isolated from human kidney, is a histone deacetylase that shares homology to other HDACs but has different tissue distribution. HDAC8 is localized to the nucleus and plays a role in the development of a broad range of tissues and in the etiology of cancer.

Long Name

Histone deacetylase 9

Alternate Names

HD7b, HD9, HDAC7, HDAC7B, HDRP, KIAA0744, MITR

Gene Symbol

HDAC9

Additional HDAC9 Products

Product Documents for HDAC9 Antibody (S01-8I6)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for HDAC9 Antibody (S01-8I6)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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