HECTD1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-82926

Novus Biologicals, part of Bio-Techne
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NBP1-82926
NBP1-82926-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (97%), Rat (96%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all HECTD1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: RHWKLTGTNKSIRKNRNCSQLIAAYKDFCEHGTKSGLNQGAISTLQSSDILNLTKEQPQAKAGNGQNSCGVEDVLQLLRILYIVASDPYSRISQEDGDEQPQFTFPPDE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for HECTD1 Antibody

Immunocytochemistry/ Immunofluorescence: HECTD1 Antibody [NBP1-82926]

Immunocytochemistry/ Immunofluorescence: HECTD1 Antibody [NBP1-82926]

Immunocytochemistry/Immunofluorescence: HECTD1 Antibody [NBP1-82926] - Staining of human cell line Hep G2 shows localization to nucleus, nucleoli & cytosol. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: HECTD1 Antibody [NBP1-82926]

Immunohistochemistry-Paraffin: HECTD1 Antibody [NBP1-82926]

Immunohistochemistry-Paraffin: HECTD1 Antibody [NBP1-82926] - Staining of human cerebral cortex shows moderate positivity in neurons.

Applications for HECTD1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF,Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HECTD1

The HECTD1 gene encodes a2, 610 amino acid long, 298 kDA E3 ubiquitin-protein ligase HECTD1 protein that accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester. It then directly transmits the ubiquitin to targeted substrates and may be essential for development of the head mesenchyme and neural tube closure. HECTD1 interacts in interferon signaling and cytokine signaling in the immune system and is known to interact with various genes such as NME2, ERCC2, PITX2, CCNA2, and NME1-NME2. HECTD1 has been investigated in many diseases such as angelman syndrome, teratoma, carcinoma, malaria, and influenza.

Alternate Names

E3 ligase for inhibin receptor, E3 ubiquitin-protein ligase HECTD1, EC 6.3.2.-, EULIR, HECT domain containing 1, HECT domain-containing protein 1, KIAA1131FLJ38315

Gene Symbol

HECTD1

Additional HECTD1 Products

Product Documents for HECTD1 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for HECTD1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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