HERPUD1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-16809

Novus Biologicals, part of Bio-Techne
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NBP2-16809
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Key Product Details

Species Reactivity

Human, Mouse

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all HERPUD1 Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human HERPUD1. The exact sequence is proprietary.

Reactivity Notes

Rat (83%), Bovine (87%).

Localization

Endoplasmic reticulum membrane; Single-pass membrane protein

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

44 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for HERPUD1 Antibody

Western Blot: HERPUD1 Antibody [NBP2-16809]

Western Blot: HERPUD1 Antibody [NBP2-16809]

Western Blot: HERPUD1 Antibody [NBP2-16809] - Sample (50 ug of whole cell lysate) A: Mouse Brain, 10% SDS PAGE gel, diluted at 1:1000.
Immunohistochemistry-Paraffin: HERPUD1 Antibody [NBP2-16809]

Immunohistochemistry-Paraffin: HERPUD1 Antibody [NBP2-16809]

Immunohistochemistry-Paraffin: HERPUD1 Antibody [NBP2-16809] - U251 xenograft, using HERPUD1 antibody at 1:500 dilution. Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min.
Western Blot: HERPUD1 Antibody [NBP2-16809]

Western Blot: HERPUD1 Antibody [NBP2-16809]

Western Blot: HERPUD1 Antibody [NBP2-16809] - Sample (30 ug of whole cell lysate) A: 293T 7. 5% SDS PAGE gel, diluted at 1:5000.

Applications for HERPUD1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:1000-1:10000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol, 1% BSA

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: HERPUD1

The accumulation of unfolded proteins in the endoplasmic reticulum (ER) triggers the ER stress response. This response includes the inhibition of translation to prevent further accumulation of unfolded proteins, the increased expression of proteins involved in polypeptide folding, known as the unfolded protein response (UPR), and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system. This gene may play a role in both UPR and ERAD. Its expression is induced by UPR and it has an ER stress response element in its promoter region while the encoded protein has an N-terminal ubiquitin-like domain which may interact with the ERAD system. This protein has been shown to interact with presenilin proteins and to increase the level of amyloid-beta protein following its overexpression. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms. The full-length nature of all transcript variants has not been determined. [provided by RefSeq]

Alternate Names

HERPMIF1, homocysteine-inducible endoplasmic reticulum stress-inducible ubiquitin-likedomain member 1 protein, homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-likedomain member 1, homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domainmember 1 protein, KIAA0025MMS-inducible, Methyl methanesulfonate (MMF)-inducible fragment protein 1, Mif1, SUP

Gene Symbol

HERPUD1

UniProt

Q15011 (Human)

Additional HERPUD1 Products

Product Documents for HERPUD1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for HERPUD1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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