HES6 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-87563

Novus Biologicals, part of Bio-Techne
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NBP2-87563
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

1 mg/ml

View all HES6 Antibodies »

Product Specifications

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of human HES6. Peptide sequence: PPGPGDDLCSDLEEAPEAELSQAPAEGPDLVPAALGSLTTAQIARSVWRP The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for HES6 Antibody

Western Blot: HES6 Antibody [NBP2-87563]

Western Blot: HES6 Antibody [NBP2-87563]

Western Blot: HES6 Antibody [NBP2-87563] - WB Suggested Anti-HES6 Antibody Titration: 1.25ug/ml. Positive Control: Transfected 293T
Immunohistochemistry: HES6 Antibody [NBP2-87563]

Immunohistochemistry: HES6 Antibody [NBP2-87563]

Immunohistochemistry: HES6 Antibody [NBP2-87563] - Human Pancreas

Applications for HES6 Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HES6

HES6 is a transcription cofactor that itself does not bind to DNA but suppresses both HES1-mediated N box-dependent transcriptional repression and binding of HES1 to E box sequences. It also suppresses HES1-mediated inhibition of the heterodimer formed by ASCL1/MASH1 and TCFEA2/E47, allowing ASCL1 and TCFEA2 to upregulate transcription in its presence. HES6 appears to have novel functions in tumor and cancer cell lines, although these have not yet been elucidated fully.

Alternate Names

BHLHB41, bHLHb41Class B basic helix-loop-helix protein 41, bHLHc23, C-HAIRY1, Hairy and enhancer of split 6, hairy and enhancer of split 6 (Drosophila), HES-6, transcription cofactor HES-6

Gene Symbol

HES6

Additional HES6 Products

Product Documents for HES6 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for HES6 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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