HFE Antibody (2O7D2)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-15323

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-15323-100ul
NBP3-15323-20ul
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 2O7D2

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all HFE Antibodies »

Product Specifications

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 249-348 of human HFE (Q30201). KEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for HFE Antibody (2O7D2)

Western Blot: HFE Antibody (2O7D2) [NBP3-15323]

Western Blot: HFE Antibody (2O7D2) [NBP3-15323]

Western Blot: HFE Antibody (2O7D2) [NBP3-15323] - Western blot analysis of extracts of various cell lines, using HFE antibody (NBP3-15323) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Applications for HFE Antibody (2O7D2)

Application
Recommended Usage

Western Blot

1:500 - 1:1000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 0.05% BSA, 50% glycerol, pH7.3

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: HFE

HFE is encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined.

Long Name

Homeostatic Iron Regulator

Alternate Names

HFE1, HLA-H, MVCD7, TFQTL2

Gene Symbol

HFE

Additional HFE Products

Product Documents for HFE Antibody (2O7D2)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for HFE Antibody (2O7D2)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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