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HIPK3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-84950

Novus Biologicals, part of Bio-Techne
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NBP1-84950
NBP1-84950-25ul

Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: SHLNSCDTNNHNKTSLLRPVASSSTATLTANFTKIGTLRSQALTTSAHSVVHHGIPLQAGTAQFGCGDAFQQTLIICPPAIQGIPA

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (85%), Rat (85%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for HIPK3 Antibody

Immunocytochemistry/ Immunofluorescence: HIPK3 Antibody [NBP1-84950]

Immunocytochemistry/ Immunofluorescence: HIPK3 Antibody [NBP1-84950]

Immunocytochemistry/Immunofluorescence: HIPK3 Antibody [NBP1-84950] - Immunofluorescent staining of human cell line U-251 MG shows localization to cytosol.
Immunohistochemistry-Paraffin: HIPK3 Antibody [NBP1-84950]

Immunohistochemistry-Paraffin: HIPK3 Antibody [NBP1-84950]

Immunohistochemistry-Paraffin: HIPK3 Antibody [NBP1-84950] - Staining of human kidney shows strong nuclear positivity in cells in tubules.

Applications for HIPK3 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HIPK3

Seems to negatively regulate apoptosis by promoting FADD phosphorylation. Enhances androgen receptor-mediated transcription. May act as a transcriptional corepressor for NK homeodomain transcription factors

Alternate Names

Androgen receptor-interacting nuclear protein kinase, DYRK6Fas-interacting serine/threonine-protein kinase, EC 2.7.11.1, FIST, FIST3ANPK, homeodomain interacting protein kinase 3, homeodomain-interacting protein kinase 3, PKYHomolog of protein kinase YAK1, YAK1

Gene Symbol

HIPK3

Additional HIPK3 Products

Product Documents for HIPK3 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for HIPK3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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