HIRA Antibody (6Q7Y6)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-16716

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-16716-100ul
NBP3-16716-20ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 6Q7Y6

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all HIRA Antibodies »

Product Summary for HIRA Antibody (6Q7Y6)

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 550-675 of human HIRA (P54198). PSVLTTPSKIEPMKAFDSRFTERSKATPGAPALTSMTPTAVERLKEQNLVKELRPRDLLESSSDSDEKVPLAKASSLSKRKLELEVETVEKKKKGRPRKDSRLMPVSLSVQSPAALTAEKEAMCLS

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for HIRA Antibody (6Q7Y6)

Western Blot: HIRA Antibody (6Q7Y6) [NBP3-16716]

Western Blot: HIRA Antibody (6Q7Y6) [NBP3-16716]

Western Blot: HIRA Antibody (6Q7Y6) [NBP3-16716] - Western blot analysis of extracts of various cell lines, using HIRA antibody (NBP3-16716) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.

Applications for HIRA Antibody (6Q7Y6)

Application
Recommended Usage

Western Blot

1:500 - 1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 0.05% BSA, 50% glycerol, pH7.3

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: HIRA

HIRA encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development. [provided by RefSeq]

Alternate Names

DGCR1DiGeorge critical region gene 1, HIR, HIR (histone cell cycle regulation defective) homolog A (S. cerevisiae), HIR histone cell cycle regulation defective homolog A (S. cerevisiae), TUP1, TUP1-like enhancer of split protein 1, TUPLE1protein HIRA

Gene Symbol

HIRA

Additional HIRA Products

Product Documents for HIRA Antibody (6Q7Y6)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for HIRA Antibody (6Q7Y6)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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