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HIV-1 gp120 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-06424

Novus Biologicals, part of Bio-Techne
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NBP3-06424-50ul

Key Product Details

Species Reactivity

Validated:

Virus

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for HIV-1 gp120 Antibody

Immunogen

Produced in rabbits immunized with purified, recombinant HIV-1(group P, strain RBF168) gp120 (ACY40659.1; Tyr38-Arg527).

Reactivity Notes

Human Immunodeficiency Virus type 1 (group P, strain RBF168)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for HIV-1 gp120 Antibody

Western Blot: HIV-1 gp120 Antibody [NBP3-06424]

Western Blot: HIV-1 gp120 Antibody [NBP3-06424]

Western Blot: HIV-1 gp120 Antibody [NBP3-06424] - Anti-S3-HIV1Pgp120-His rabbit polyclonal antibody at 1:1000 dilution. Sample:S3-HIV1Pgp120-His Recombinant Protein. Lane A: 30ng. Secondary: HRP Conjugated Goat anti-rabbit IgG (H+L) at 1/1000 dilution. Performed under reducing conditions.

Applications for HIV-1 gp120 Antibody

Application
Recommended Usage

ELISA

1:5000-1:10000

Western Blot

1:1000-1:5000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HIV-1 gp120

HIV-1 gp120 is a surface glycoprotein that enables viral attachment and entry into host cells. It is also involved in neurotoxicity and has been implicated in HIV-associated neurocognitive disorders. HIV-1 gp120 also induces apoptosis in neuronal cells by signaling mitochondrial-death proteins which may upregulate the death receptor, Fas. Because HIV gp120 is necessary for HIV-1 to enter CD4 cells, gp120 is one of the main targets of HIV vaccine research.

Alternate Names

Envelope surface glycoprotein gp120, gp120, gp120 glycoprotein, Human immunodeficiency virus 1, SU, Surface protein

Gene Symbol

env

Additional HIV-1 gp120 Products

Product Documents for HIV-1 gp120 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for HIV-1 gp120 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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