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HIV-1 gp41 Antibody (425D11.01/ clone 3)

Novus Biologicals, part of Bio-Techne | Catalog # DDX1306

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Virus

Applications

ELISA, Flow Cytometry, Inhibition Activity, Neutralization, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 425D11.01/ clone 3

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

HR1-PID-HR2-transfected HEK 293 cells (HIV-1, 92BR025, Clade C)

Reactivity Notes

virus

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for HIV-1 gp41 Antibody (425D11.01/ clone 3)

Western Blot: HIV-1 gp41 Antibody (425D11.01/ clone 3) [DDX1306]

Western Blot: HIV-1 gp41 Antibody (425D11.01/ clone 3) [DDX1306]

Western Blot: HIV-1 gp41 Antibody (425D11.01/ clone 3) [DDX1306] - Analysis of a purified multi-epitopic HIV antigen. The expected length of the HIV protein is 20 kDa. The second signal might represent a by-product.
Flow Cytometry: HIV-1 gp41 Antibody (425D11.01/ clone 3) [DDX1306]

Flow Cytometry: HIV-1 gp41 Antibody (425D11.01/ clone 3) [DDX1306]

Flow Cytometry: HIV-1 gp41 Antibody (425D11.01/ clone 3) [DDX1306] - FACS staining of HEK293-gp41TM cell line
Inhibition Activity: HIV-1 gp41 Antibody (425D11.01/ clone 3) [DDX1306]

Inhibition Activity: HIV-1 gp41 Antibody (425D11.01/ clone 3) [DDX1306]

Inhibition Activity: HIV-1 gp41 Antibody (425D11.01/ clone 3) [DDX1306] - Inhibition of HR1/HR2 fusion complex formation

Applications for HIV-1 gp41 Antibody (425D11.01/ clone 3)

Application
Recommended Usage

ELISA

1:100-1:2000

Flow Cytometry

1:10-1:1000

Western Blot

1:100-1:2000
Application Notes
Flow Cytometry, ELISA
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Ion exchange chromatography

Formulation

Tris-NaCl (pH 8.0)

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C in the dark. Avoid freeze-thaw cycles.

Background: HIV-1 gp41

HIV1 performs highly complex orchestrated tasks during the assembly, budding, maturation and infection stages of the viral replication cycle. During viral assembly, the proteins form membrane associations and self associations that ultimately result in budding of an immature virion from the infected cell. Gag precursors also function during viral assembly to selectively bind and package two plus strands of genomic RNA. Capsid protein p24 probably forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex.

Alternate Names

Env, Glycoprotein 41, gp41, Human immunodeficiency virus 1, Human Immunodeficiency Virus Type 1 gp41, TM, Transmembrane protein

Additional HIV-1 gp41 Products

Product Documents for HIV-1 gp41 Antibody (425D11.01/ clone 3)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for HIV-1 gp41 Antibody (425D11.01/ clone 3)

This product is manufactured by Eurobio Scientific (formerly Dendritics) and distributed by Novus Biologicals.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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