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HLA Class I Antibody (mAb90)

Novus Biologicals, part of Bio-Techne | Catalog # DDX0250P-100

Novus Biologicals, part of Bio-Techne
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DDX0250P-100

Key Product Details

Validated by

Biological Validation

Species Reactivity

Human

Applications

ELISA, Flow Cytometry, Functional

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # mAb90

Concentration

0.5 mg/ml

Product Specifications

Immunogen

HLA-A1 was used as immunogen.

Reactivity Notes

Human

Specificity

human alpha1domain of HLA class I molecule

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for HLA Class I Antibody (mAb90)

Functional: HLA Class I Antibody (mAb90) [DDX0250P-100]

Functional: HLA Class I Antibody (mAb90) [DDX0250P-100]

Functional: HLA Class I Antibody (mAb90) [DDX0250P-100] - mAb90 inhibits CD40-dependent B-cell proliferation. Tonsil B cells were cultured for 5 days on CD32-L cellsi n the presence of 1ug/ml anti-CD40 mAb with 1ug/ml of W6/32 or mAb90.
Functional: HLA Class I Antibody (mAb90) [DDX0250P-100]

Functional: HLA Class I Antibody (mAb90) [DDX0250P-100]

Functional: HLA Class I Antibody (mAb90) [DDX0250P-100] - mAb90 induces apoptosis of CD40-activated B cells. Cells were collected after 12 hours of treatment with the different mAbs and DNA from 2X104 cells was runon 2% agarose gel and stainedwith ethidiumbromide.

Applications for HLA Class I Antibody (mAb90)

Application
Recommended Usage

ELISA

1:100-1:2000

Flow Cytometry

1:10-1:1000

Formulation, Preparation, and Storage

Purification

Ion exchange chromatography

Formulation

Tris-NaCl (pH 8.0)

Preservative

No Preservative

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: HLA Class I

HLA CLass I is involved in the presentation of foreign antigens to the immune system. This antibody is a valuable reagent for analysing variations in HLA class I expression in different disease states e.g. liver disease, muscular dystrophy, inflammatory myopathy and other neuromuscular disorders. This antibody is also suitable as a positive control for HLA tissue typing and crossmatching.

Long Name

Class I Human Leukocyte Antigen

Alternate Names

HLA-A, HLA-ABC

Gene Symbol

HLA-A

Additional HLA Class I Products

Product Documents for HLA Class I Antibody (mAb90)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for HLA Class I Antibody (mAb90)

This product is manufactured by Eurobio Scientific (formerly Dendritics) and distributed by Novus Biologicals.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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