HLA DMA Antibody (3F12-F11)

Novus Biologicals, part of Bio-Techne | Catalog # H00003108-M01

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 3F12-F11

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all HLA DMA Antibodies »

Product Specifications

Immunogen

HLA-DMA (AAH11447, 1 a.a. ~ 261 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MGHEQNQGAALLQMLPLLWLLPHSWAVPEAPTPMWPDDLQNHTFLHTVYCQDGSPSVGLSEAYDEDQLFFFDFSQNTRVPRLPEFADWAQEQGDAPAILFDKEFCEWMIQQIGPKLDGKIPVSRGFPIAEVFTLKPLEFGKPNTLVCFVSNLFPPMLTVNWQHHSVPVEGFGPTFVSAVDGLSFQAFSYLNFTPEPSDIFSCIVTHEIDRYTAIAYWVPRNALPSDLLENVLCGVAFGLGVLGIIVGIVLIIYFRKPCSGD

Specificity

HLA-DMA - major histocompatibility complex, class II, DM alpha

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for HLA DMA Antibody (3F12-F11)

Western Blot: HLA DMA Antibody (3F12-F11) [H00003108-M01]

Western Blot: HLA DMA Antibody (3F12-F11) [H00003108-M01]

Western Blot: HLA DMA Antibody (3F12-F11) [H00003108-M01] - HLA-DMA monoclonal antibody (M01), clone 3F12-F11 Analysis of HLA-DMA expression in U-2 OS.
Immunohistochemistry-Paraffin: HLA DMA Antibody (3F12-F11) [H00003108-M01]

Immunohistochemistry-Paraffin: HLA DMA Antibody (3F12-F11) [H00003108-M01]

Immunohistochemistry-Paraffin: HLA DMA Antibody (3F12-F11) [H00003108-M01] - Analysis of monoclonal antibody to HLA-DMA on formalin-fixed paraffin-embedded human malignant lymphoma, diffuse large B tissue. Antibody concentration 3 ug/ml.
ELISA: HLA DMA Antibody (3F12-F11) [H00003108-M01]

ELISA: HLA DMA Antibody (3F12-F11) [H00003108-M01]

ELISA: HLA DMA Antibody (3F12-F11) [H00003108-M01] - Detection limit for recombinant GST tagged HLA-DMA is approximately 3ng/ml as a capture antibody.
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Applications for HLA DMA Antibody (3F12-F11)

Application
Recommended Usage

Western Blot

1:500

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: HLA DMA

HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB), both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail.

Alternate Names

class II histocompatibility antigen, M alpha chain, D6S222E, DMA, HLA class II histocompatibility antigen, DM alpha chain, major histocompatibility complex, class II, DM alpha, MHC class II antigen DMA, Really interesting new gene 6 protein, RING6HLADM

Entrez Gene IDs

3108 (Human)

Gene Symbol

HLA-DMA

OMIM

142855 (Human)

UniProt

AAH11447 (Human)

Additional HLA DMA Products

Product Documents for HLA DMA Antibody (3F12-F11)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for HLA DMA Antibody (3F12-F11)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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