HLA DPA Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-89689

Novus Biologicals, part of Bio-Techne
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NBP1-89689
NBP1-89689-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all HLA DPA Antibodies »

Product Summary for HLA DPA Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: RPTGEFMFEFDEDEMFYVDLDKKETVWHLEEFGQAFSFEAQGGLANIAILNNNLNTLIQRSNHTQATNDPPEVTVFPKEPVELGQPNTLICHIDKFFPPVLNVTWLCNGELVTEGVAESLFLPRTDYSFHKFHYLTF

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for HLA DPA Antibody

Immunohistochemistry-Paraffin: HLA DPA Antibody [NBP1-89689]

Immunohistochemistry-Paraffin: HLA DPA Antibody [NBP1-89689]

Immunohistochemistry-Paraffin: HLA DPA Antibody [NBP1-89689] - Staining in human lymph node and cerebral cortex tissues using anti-HLA-DPA1 antibody. Corresponding HLA-DPA1 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: HLA DPA Antibody [NBP1-89689]

Immunohistochemistry-Paraffin: HLA DPA Antibody [NBP1-89689]

Immunohistochemistry-Paraffin: HLA DPA Antibody [NBP1-89689] - Staining of human cerebral cortex shows low expression as expected.
Immunohistochemistry-Paraffin: HLA DPA Antibody [NBP1-89689]

Immunohistochemistry-Paraffin: HLA DPA Antibody [NBP1-89689]

Immunohistochemistry-Paraffin: HLA DPA Antibody [NBP1-89689] - Staining of human lymph node shows high expression.

Applications for HLA DPA Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HLA DPA

HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. [provided by RefSeq]

Alternate Names

DP alpha 1 chain, HLA class II histocompatibility antigen, DP alpha chain, HLADP, HLA-SB alpha chain, major histocompatibility complex, class II, DP alpha 1, MHC class II antigen, MHC class II DP3-alpha, MHC class II DPA1, MHC class II HLA-DPA1 antigen, Primed lymphocyte test-1

Gene Symbol

HLA-DPA1

Additional HLA DPA Products

Product Documents for HLA DPA Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for HLA DPA Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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