HLA DPB1 Antibody (6C6)

Novus Biologicals, part of Bio-Techne | Catalog # H00003115-M01

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 6C6

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all HLA DPB1 Antibodies »

Product Specifications

Immunogen

HLA-DPB1 (AAH13184, 1 a.a. ~ 258 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MMVLQVSAAPRTVALTALLMVLLTSVVQGRATPENYVYQGRQECYAFNGTQRFLERYIYNREEYARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRVCRHNYELDEAVTLQRRVQPKVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRNGDWTFQILVMLEMTPQQGDVYICQVEHTSLDSPVTVEWKAQSDSAQSKTLTGAGGFVLGLIICGVGIFMHRRSKKVQRGSA

Specificity

HLA-DPB1 - major histocompatibility complex, class II, DP beta 1

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for HLA DPB1 Antibody (6C6)

Western Blot: HLA DPB1 Antibody (6C6) [H00003115-M01]

Western Blot: HLA DPB1 Antibody (6C6) [H00003115-M01]

Western Blot: HLA DPB1 Antibody (6C6) [H00003115-M01] - Analysis of HLA-DPB1 expression in transfected 293T cell line by HLA-DPB1 monoclonal antibody (M01), clone 6C6.Lane 1: HLA-DPB1 transfected lysate(29 KDa).Lane 2: Non-transfected lysate.
Immunohistochemistry-Paraffin: HLA DPB1 Antibody (6C6) [H00003115-M01]

Immunohistochemistry-Paraffin: HLA DPB1 Antibody (6C6) [H00003115-M01]

Immunohistochemistry-Paraffin: HLA DPB1 Antibody (6C6) [H00003115-M01] - Analysis of monoclonal antibody to HLA-DPB1 on formalin-fixed paraffin-embedded human lymph node. Antibody concentration 0.5 ug/ml.
Immunoprecipitation: HLA DPB1 Antibody (6C6) [H00003115-M01]

Immunoprecipitation: HLA DPB1 Antibody (6C6) [H00003115-M01]

Immunoprecipitation: HLA DPB1 Antibody (6C6) [H00003115-M01] - Analysis of HLA-DPB1 transfected lysate using anti-HLA-DPB1 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with HLA-DPB1 monoclonal antibody.
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Applications for HLA DPB1 Antibody (6C6)

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Immunoprecipitation

1:10-1:500

Western Blot

1:500
Application Notes
Antibody reactivity against transfected lysate and recombinant protein for WB.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: HLA DPB1

HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.

Alternate Names

DP beta 1 chain, DPB1, HLA class II histocompatibility antigen, DP(W4) beta chain, HLA DP14-beta chain, HLA-DP histocompatibility type, beta-1 subunit, HLA-DP1B, HLA-DPB, major histocompatibility complex class II HLA DPB1 protein, major histocompatibility complex, class II, DP beta 1, MHC class II antigen beta chain, MHC class II antigen DP beta 1 chain, MHC class II antigen DPB1, MHC class II antigen DPbeta1, MHC class II HLA-DP-beta, MHC HLA DPB1

Entrez Gene IDs

3115 (Human)

Gene Symbol

HLA-DPB1

OMIM

142858 (Human)

UniProt

AAH13184 (Human)

Additional HLA DPB1 Products

Product Documents for HLA DPB1 Antibody (6C6)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for HLA DPB1 Antibody (6C6)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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