HMBS Antibody (8G12)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-26225

Recombinant monoclonal antibody expressed in HEK293F cells
Novus Biologicals, part of Bio-Techne
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NBP3-26225-100ul
NBP3-26225-50ul
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 8G12

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all HMBS Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from Human HMBS [UniProt P08397]

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for HMBS Antibody (8G12)

HMBS Antibody (8G12)

Western Blot: HMBS Antibody (8G12) [NBP3-26225] -

Western Blot: HMBS Antibody (8G12) [NBP3-26225] - Positive Western Blot detected in: MCF-7 whole cell lysate, K562 whole cell lysate, Jurkat whole cell lysate, THP-1 whole cell lysate, U937 whole cell lysate.
All lanes: HMBS Antibody at 1: 2000
Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution.
Predicted band size: 40, 38, 35, 34kDa
Observed band size: 36-55 kDa

Applications for HMBS Antibody (8G12)

Application
Recommended Usage

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl and 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20 to -70C. Avoid freeze-thaw cycles.

Background: HMBS

HMBS encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described.

Alternate Names

hydroxymethylbilane synthasePre-uroporphyrinogen synthase, PBGDPBG-D, PORC, porphobilinogen deaminase, porphyria, acute; Chester type, UPSEC 2.5.1.61, uroporphyrinogen I synthase, uroporphyrinogen I synthetase

Gene Symbol

HMBS

Additional HMBS Products

Product Documents for HMBS Antibody (8G12)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for HMBS Antibody (8G12)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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