HMGA2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-48699

Novus Biologicals, part of Bio-Techne
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NBP2-48699
NBP2-48699-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Predicted:

Mouse (97%), Rat (97%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all HMGA2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: MSARGEGAGQPSTSAQGQPAAPAPQKRGR

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for HMGA2 Antibody

Immunohistochemistry-Paraffin: HMGA2 Antibody [NBP2-48699]

Immunohistochemistry-Paraffin: HMGA2 Antibody [NBP2-48699]

Immunohistochemistry-Paraffin: HMGA2 Antibody [NBP2-48699] - Staining of human rectum shows moderate nuclear positivity in glandular cells.
Immunohistochemistry-Paraffin: HMGA2 Antibody [NBP2-48699]

Immunohistochemistry-Paraffin: HMGA2 Antibody [NBP2-48699]

Immunohistochemistry-Paraffin: HMGA2 Antibody [NBP2-48699] - Staining of human testis shows strong nuclear positivity in cells in seminiferous ducts.
Immunohistochemistry-Paraffin: HMGA2 Antibody [NBP2-48699]

Immunohistochemistry-Paraffin: HMGA2 Antibody [NBP2-48699]

Immunohistochemistry-Paraffin: HMGA2 Antibody [NBP2-48699] - Staining of human testis shows moderate to strong nuclear positivity in cells in seminiferous ducts.
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Applications for HMGA2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000

Western Blot

0.04 - 0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Use in Western Blot reported in scientific literature (PMID:33078654).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HMGA2

HMGA2 encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Long Name

High Mobility Group AT-hook 2

Alternate Names

BABL, HMGIC, LIPO

Gene Symbol

HMGA2

Additional HMGA2 Products

Product Documents for HMGA2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for HMGA2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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