HNF-6/ONECUT1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-27079

Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
NBP2-27079
NBP2-27079SS
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Species Reactivity

Validated:

Human, Canine, Primate

Predicted:

Bovine (94%), Chimpanzee (100%), Monkey (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all HNF-6/ONECUT1 Antibodies »

Product Specifications

Immunogen

A portion of amino acids 420-465 of human HNF6 was used as the immunogen.

Reactivity Notes

The amino acid sequence used as immunogen is 88% homologous in Mouse and Opossum, and 82% homologous in Zebrafish.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for HNF-6/ONECUT1 Antibody

Western Blot: HNF-6/ONECUT1 Antibody [NBP2-27079]

Western Blot: HNF-6/ONECUT1 Antibody [NBP2-27079]

Western Blot: HNF-6/ONECUT1 Antibody [NBP2-27079] - Analysis ofHNF6 inhuman pancreas in the 1) absence and 2) presence of immunizing peptide, and 3) rat pancreasusing this antibody. Goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.
Immunohistochemistry-Paraffin: HNF-6/ONECUT1 Antibody [NBP2-27079]

Immunohistochemistry-Paraffin: HNF-6/ONECUT1 Antibody [NBP2-27079]

Immunohistochemistry-Paraffin: HNF-6/ONECUT1 Antibody [NBP2-27079] - Analysis of HNF6 in formalin-fixed, paraffin-embedded human liver tissue using an isotype control (top) and this antibody (bottom) at 5 ug/ml.

Applications for HNF-6/ONECUT1 Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

5ug/ml

Western Blot

3-5ug/ml~

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

0.2 ml PBS and 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HNF-6/ONECUT1

Hepatocyte nuclear factor 6 is a CUT homeobox family protein which is a transcription factor and contains a CUT DNA-binding domain and a homeobox DNA-binding domain. It is an upstream regulator of several genes involved in the pathogenesis of maturity-onset diabetes of the young. HNF6 is a ligand of the FOXM1 transcription factor network. HNF6, along with HNF4, controls gene expression in the liver. The expression levels of HNF6 and HNF4 rise steadily during development and that up- or down regulation of HNF6 and HNF4 expression generate premature or delayed expression of the g6pc gene.

Long Name

Hepatocyte Nuclear Factor 6

Alternate Names

HNF-6A, HNF6, OC-1, ONECUT1

Gene Symbol

ONECUT1

UniProt

Q9UBC0 (Human)

Additional HNF-6/ONECUT1 Products

Product Documents for HNF-6/ONECUT1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for HNF-6/ONECUT1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.