HPS4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-31898

Novus Biologicals, part of Bio-Techne
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NBP2-31898
NBP2-31898-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all HPS4 Antibodies »

Product Summary for HPS4 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: GQRGNKLPTGEQGLDEDVDGVCESHAAPGLECSSGSANCQGAGPSADGISSRLTPAESCMGLVRMNLYTHCVKGLVLSLLAEEPLLGDSAAIEEVYHSSLASLNGLEVHLKETLPRDEAASTSSTYNFTHYDR

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for HPS4 Antibody

Immunocytochemistry/ Immunofluorescence: HPS4 Antibody [NBP2-31898]

Immunocytochemistry/ Immunofluorescence: HPS4 Antibody [NBP2-31898]

Immunocytochemistry/Immunofluorescence: HPS4 Antibody [NBP2-31898] - Immunofluorescent staining of human cell line A-431 shows localization to centrosome.
Immunohistochemistry: HPS4 Antibody [NBP2-31898]

Immunohistochemistry: HPS4 Antibody [NBP2-31898]

Immunohistochemistry: HPS4 Antibody [NBP2-31898] - Staining of human stomach shows strong cytoplasmic positivity in glandular cells.

Applications for HPS4 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HPS4

Hermansky-Pudlak syndrome is a disorder of organelle biogenesis in which oculocutaneous albinism, bleeding, and pulmonary fibrosis result from defects of melanosomes, platelet dense granules, and lysosomes. Mutations in this gene as well as several others can cause this syndrome. The protein encoded by this gene appears to be important in organelle biogenesis and is similar to the mouse 'light ear' protein. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]. Transcript Variant: This variant (1) encodes the longer isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Alternate Names

bK1048E9.4, Hermansky-Pudlak syndrome 4, Hermansky-Pudlak syndrome 4 protein, KIAA1667bK1048E9.5, LE, Light-ear protein homolog

Gene Symbol

HPS4

UniProt

Q9NQG7 (Human)

Additional HPS4 Products

Product Documents for HPS4 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for HPS4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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