HR6A/UBE2A Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-54946

Novus Biologicals, part of Bio-Techne
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NBP2-54946
NBP2-54946-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all HR6A/UBE2A Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: IQSLLDEPNPNSPANSQAAQLYQENKREYEKRVSAIVEQSW

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for HR6A/UBE2A Antibody

Western Blot: HR6A/UBE2A Antibody [NBP2-54946]

Western Blot: HR6A/UBE2A Antibody [NBP2-54946]

Western Blot: HR6A/UBE2A Antibody [NBP2-54946] - Western blot analysis in human cell line RT-4, human cell line U-251 MG, human plasma, human liver tissue and human tonsil tissue.
Immunocytochemistry/ Immunofluorescence: HR6A/UBE2A Antibody [NBP2-54946]

Immunocytochemistry/ Immunofluorescence: HR6A/UBE2A Antibody [NBP2-54946]

Immunocytochemistry/Immunofluorescence: HR6A/UBE2A Antibody [NBP2-54946] - Staining of human cell line A-431 shows localization to nucleoplasm & vesicles.

Applications for HR6A/UBE2A Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Western Blot

0.04-0.4 ug/ml
Application Notes
Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HR6A/UBE2A

Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Coactivates expression in an agonist- and AF2-dependent manner. Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ERs), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). Probably functions as a general coactivator, rather than just a nuclear receptor coactivator. May also be involved in the coactivation of the NF-kappa-B pathway. May coactivate expression via a remodeling of chromatin and its interaction with histone acetyltransferase proteins. Involved in placental, cardiac, hepatic and embryonic development. NCOA6 is over-expressed in several breast cancer cell lines.

Long Name

Ubiquitin-conjugating Enzyme E2A

Alternate Names

RAD6A, UBE2A

Gene Symbol

UBE2A

Additional HR6A/UBE2A Products

Product Documents for HR6A/UBE2A Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for HR6A/UBE2A Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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