HSD17B3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-38807

Novus Biologicals, part of Bio-Techne
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NBP2-38807
NBP2-38807-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all HSD17B3 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: NVGILPNLLPSHFLNAPDEIQSLIHCNITSVVKMTQLILKHMESRQKGLIL

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Rat (80%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for HSD17B3 Antibody

Immunohistochemistry-Paraffin: HSD17B3 Antibody [NBP2-38807]

Immunohistochemistry-Paraffin: HSD17B3 Antibody [NBP2-38807]

Immunohistochemistry-Paraffin: HSD17B3 Antibody [NBP2-38807] - Analysis in human testis and skin tissues using NBP2-38807 antibody. Corresponding HSD17B3 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: HSD17B3 Antibody [NBP2-38807]

Immunohistochemistry-Paraffin: HSD17B3 Antibody [NBP2-38807]

Immunohistochemistry-Paraffin: HSD17B3 Antibody [NBP2-38807] - Staining of human skin shows negative cytoplasmic positivity in keratinocytes as expected.
Immunohistochemistry-Paraffin: HSD17B3 Antibody [NBP2-38807]

Immunohistochemistry-Paraffin: HSD17B3 Antibody [NBP2-38807]

Immunohistochemistry-Paraffin: HSD17B3 Antibody [NBP2-38807] - Staining of human testis shows high expression.
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Applications for HSD17B3 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HSD17B3

HSD17B3 is an isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia.

Alternate Names

EC 1.1.1.64, EDH17B317-beta-HSD3, hydroxysteroid (17-beta) dehydrogenase 3,17-beta-hydroxysteroid dehydrogenase type 3, SDR12C2, short chain dehydrogenase/reductase family 12C, member 2, Testicular 17-beta-hydroxysteroid dehydrogenase, testosterone 17-beta-dehydrogenase 3,17-beta-HSD 3

Gene Symbol

HSD17B3

UniProt

P37058 (Human)

Additional HSD17B3 Products

Product Documents for HSD17B3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for HSD17B3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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