Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat, Porcine, Bovine, Canine, Guinea Pig, Hamster, Primate, Rabbit, Sheep

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

DyLight 488 (Excitation = 493 nm, Emission = 518 nm)

Antibody Source

Monoclonal Rat IgG1 Clone # 3E2

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all HSF2 Antibodies »

Product Summary for HSF2 Antibody (3E2) [DyLight 488]

Immunogen

Purified recombinant mouse HSF2 protein

Reactivity Notes

Human, Mouse, Rat, Guinea Pig, Hamster, Primate, Rabbit, Bovine, Sheep, Porcine, Canine

Localization

Cytoplasm , Nucleus

Specificity

Detects an approx. 69kDa protein in unstressed cells corresponding to HSF2 on SDS-PAGE immunoblots.

Clonality

Monoclonal

Host

Rat

Isotype

IgG1

Applications for HSF2 Antibody (3E2) [DyLight 488]

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: HSF2

Heat shock factor 1 (HSF1) is a heat shock transcription factor that activates the transcription of genes encoding products required for protein folding, processing, targeting, degradation, and function. Up-regulation of expression of heat shock proteins in response to stress occurs at the level of transcription through a heat shock element and a HSF transcription factor. Amino acid sequences for most HSFs are highly conserved. A DNA binding domain is at the N-terminus, hydrophobic repeats (essential to the formation of active trimers) are adjacent to this binding domain, and another short hydrophobic repeat (necessary for suppression of trimerization) occurs toward the C-terminus. HSF2 exists as two isoforms, the alpha form being more transcriptionally active than the smaller beta form. Various experiments have suggested that HSF2 may play roles in differentiation and development.

Long Name

Heat Shock Transcription Factor 2

Alternate Names

HSTF2

Gene Symbol

HSF2

Additional HSF2 Products

Product Documents for HSF2 Antibody (3E2) [DyLight 488]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for HSF2 Antibody (3E2) [DyLight 488]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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