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HSF2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-86330

Novus Biologicals, part of Bio-Techne
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NBP1-86330
NBP1-86330-25ul

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (91%), Rat (92%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for HSF2 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: LGKVELLDYLDSIDCSLEDFQAMLSGRQFSIDPDLLVDSENKGLETTKNNVVQPVSEEGRKSKSKPDKQLIQYTAFPLLAFLDGNPASSVEQASTTASSEVLSSVD

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for HSF2 Antibody

Immunohistochemistry-Paraffin: HSF2 Antibody [NBP1-86330]

Immunohistochemistry-Paraffin: HSF2 Antibody [NBP1-86330]

Immunohistochemistry-Paraffin: HSF2 Antibody [NBP1-86330] - Staining of human testis shows weak to moderate nuclear positivity in cells in seminiferous ducts.
Immunohistochemistry-Paraffin: HSF2 Antibody [NBP1-86330]

Immunohistochemistry-Paraffin: HSF2 Antibody [NBP1-86330]

Immunohistochemistry-Paraffin: HSF2 Antibody [NBP1-86330] - Staining of human liver shows no positivity in hepatocytes as expected.
Immunohistochemistry-Paraffin: HSF2 Antibody [NBP1-86330]

Immunohistochemistry-Paraffin: HSF2 Antibody [NBP1-86330]

Immunohistochemistry-Paraffin: HSF2 Antibody [NBP1-86330] - Staining of human cerebellum shows moderate cytoplasmic positivity in Purkinje cells.

Applications for HSF2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HSF2

Heat shock factor 1 (HSF1) is a heat shock transcription factor that activates the transcription of genes encoding products required for protein folding, processing, targeting, degradation, and function. Up-regulation of expression of heat shock proteins in response to stress occurs at the level of transcription through a heat shock element and a HSF transcription factor. Amino acid sequences for most HSFs are highly conserved. A DNA binding domain is at the N-terminus, hydrophobic repeats (essential to the formation of active trimers) are adjacent to this binding domain, and another short hydrophobic repeat (necessary for suppression of trimerization) occurs toward the C-terminus. HSF2 exists as two isoforms, the alpha form being more transcriptionally active than the smaller beta form. Various experiments have suggested that HSF2 may play roles in differentiation and development.

Long Name

Heat Shock Transcription Factor 2

Alternate Names

HSTF2

Gene Symbol

HSF2

Additional HSF2 Products

Product Documents for HSF2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for HSF2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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