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HSP90 alpha Antibody (HSP90AA1/7247) [CoraFluor™ 1]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-26954CL1

Novus Biologicals, part of Bio-Techne
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NBP3-26954CL1

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry-Paraffin

Label

CoraFluor 1

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # HSP90AA1/7247

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Recombinant fragment (around aa500-700) of human HSP90 alpha protein (exact sequence is proprietary)

Localization

Cytoplasm, Melanosome

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Description

CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.

Applications for HSP90 alpha Antibody (HSP90AA1/7247) [CoraFluor™ 1]

Application
Recommended Usage

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark. Do not freeze.

Background: HSP90 alpha

HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding,protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and playimportant roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress.There are 2 major cytosolic HSP90 proteins, HSP90AA1, an inducible form, and HSP90AB1 (MIM 140572), a constitutiveform. Other HSP90 proteins are found in endoplasmic reticulum (HSP90B1; MIM 191175) and mitochondria (TRAP1; MIM606219) (Chen et al., 2005 (PubMed 16269234)).(supplied by OMIM)

Long Name

Heat Shock Protein 90 alpha

Alternate Names

HSP86, HSP89A, HSP90A, HSP90AA1, HSP90N, HSPC1, HSPCA, HSPCAL1, HSPCAL4, HSPN, LAP2

Gene Symbol

HSP90AA1

Additional HSP90 alpha Products

Product Documents for HSP90 alpha Antibody (HSP90AA1/7247) [CoraFluor™ 1]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for HSP90 alpha Antibody (HSP90AA1/7247) [CoraFluor™ 1]

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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