HSP22 is encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.

Long Name

Heat Shock Protein beta 8

Alternate Names

CMT2L, CRYAC, DHMN2, E2IG1, H11, HMN2A, HSP22

Gene Symbol

HSPB8

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Product Documents for HSPB8/HSP22 Antibody (3C12-H11) [DyLight 650]

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COA

SDS

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Product Specific Notices for HSPB8/HSP22 Antibody (3C12-H11) [DyLight 650]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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HSPB8/HSP22 Antibody (3C12-H11) [DyLight 650]

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-48303C

Key Product Details

Species Reactivity

Applications

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Product Specifications

Immunogen

Localization

Specificity

Clonality

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Applications for HSPB8/HSP22 Antibody (3C12-H11) [DyLight 650]

ELISA

Immunocytochemistry/ Immunofluorescence

Immunohistochemistry-Paraffin

Western Blot

Formulation, Preparation, and Storage

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Formulation

Preservative

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Background: HSPB8