HspBP1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-49658

Novus Biologicals, part of Bio-Techne
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NBP2-49658
NBP2-49658-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (99%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all HspBP1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: KLKVKSAFLLQNLLVGHPEHKGTLCSMGMVQQLVALVRTEHSPFHEHVLGALCSLVTDFPQGVRECREPELGLEELLRHRCQLLQQHEEYQEELEFCEKLLQT

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for HspBP1 Antibody

Western Blot: HspBP1 Antibody [NBP2-49658]

Western Blot: HspBP1 Antibody [NBP2-49658]

Western Blot: HspBP1 Antibody [NBP2-49658] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10
Lane 2: Human cell line RT-4
Lane 3: Human cell line U-251 MG
Immunohistochemistry-Paraffin: HspBP1 Antibody [NBP2-49658]

Immunohistochemistry-Paraffin: HspBP1 Antibody [NBP2-49658]

Immunohistochemistry-Paraffin: HspBP1 Antibody [NBP2-49658] - Staining of human pancreas shows low expression as expected.
Immunohistochemistry: HspBP1 Antibody [NBP2-49658]

Immunohistochemistry: HspBP1 Antibody [NBP2-49658]

Immunohistochemistry: HspBP1 Antibody [NBP2-49658] - Staining of human testis shows strong cytoplasmic and nuclear positivity in testis.
View 1 more images

Applications for HspBP1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HspBP1

Heat shock protein binding protein is an Hsp70-interacting protein that was first isolated from a human heart cDNA library using the yeast two-hybrid system. HspBP1 binds the ATPase domain of Hsp70, and inhibits Hsp70 chaperone activity. More recently HspBP1 was found to promote nucleotide dissociation from Hsc70 and is capable of altering the confirmation of the Hsp70 ATPase domain. HspBP1 is capable of regulating any Hsp70 activity that requires ATPase.

Alternate Names

FES1, Heat shock protein-binding protein 1, Hsp70 binding protein 1, hsp70 interacting protein, hsp70-binding protein 1, Hsp70-binding protein 2, Hsp70-interacting protein 1, Hsp70-interacting protein 2, HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1, HSPBP, HspBP1, hspBP2

Gene Symbol

HSPBP1

Additional HspBP1 Products

Product Documents for HspBP1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for HspBP1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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