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htrA4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-30882

Novus Biologicals, part of Bio-Techne
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NBP2-30882
NBP2-30882-25ul

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: FAIPSDRVRQFLAEYHEHQMKGKAFSNKKYLGLQMLSLTVPLSEELKMHYPDFPDVSSG

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for htrA4 Antibody

Immunohistochemistry-Paraffin: htrA4 Antibody [NBP2-30882]

Immunohistochemistry-Paraffin: htrA4 Antibody [NBP2-30882]

Immunohistochemistry-Paraffin: htrA4 Antibody [NBP2-30882] - Analysis in human placenta and skeletal muscle tissues. Corresponding htrA4 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: htrA4 Antibody [NBP2-30882]

Immunohistochemistry-Paraffin: htrA4 Antibody [NBP2-30882]

Immunohistochemistry-Paraffin: htrA4 Antibody [NBP2-30882] - Staining of human tonsil shows no positivity in non-germinal center cells as expected.
Immunohistochemistry-Paraffin: htrA4 Antibody [NBP2-30882]

Immunohistochemistry-Paraffin: htrA4 Antibody [NBP2-30882]

Immunohistochemistry-Paraffin: htrA4 Antibody [NBP2-30882] - Staining of human placenta shows moderate cytoplasmic positivity in trophoblastic cells.

Applications for htrA4 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HTRA4

htrA4 encodes a member of the HtrA family of proteases. The encoded protein contains a putative signal peptide, an insulin growth factor binding domain, a Kazal protease inhibitor domain, a conserved trypsin domain and a PDZ domain. Based on studies on other related family members, this enzyme may function as a secreted oligomeric chaperone protease to degrade misfolded secretory proteins. Other human HtrA proteins have been implicated in arthritis, tumor suppression, unfolded stress response, apoptosis, and aging. [provided by RefSeq]

Long Name

HtrA serine peptidase 4

Alternate Names

HTRA 4

Gene Symbol

HTRA4

UniProt

Additional HTRA4 Products

Product Documents for htrA4 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for htrA4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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