NS0 mouse myeloma cell line transfected with AGTR-2 was stained with Mouse Anti-Human AGTR-2 PE-conjugated Monoclonal Antibody (Catalog # FAB3659P, filled histogram) or isotype control antibody (Catalog # IC0041P, open histogram). View our protocol for Staining Membrane-associated Proteins.

Applications for Human AGTR-2 PE-conjugated Antibody

Application

Recommended Usage

Flow Cytometry

10 µL/10⁶ cells
Sample: NS0 mouse myeloma cell line transfected with AGTR-2

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze.

12 months from date of receipt, 2 to 8 °C as supplied.

Background: AGTR-2

AGTR-2, also known as AT2, is a 7-transmembrane protein that belongs to family 1 of G protein-coupled receptors. Both AGTR-2 and AGTR-1 bind Angiotensin II and function in the control of hemodynamics. In contrast to AGTR-1, which promotes vasoconstriction and cell proliferation, AGTR-2 inhibits growth and promotes apoptosis. In addition, Angiotensin II-induced AGTR-2 signaling induces the release of nitric oxide in the heart, kidney, and brain and participates in tissue morphogenesis and repair. Human AGTR-2 shares 92% amino acid sequence identity with mouse and rat AGTR-2.

Long Name

Angiostensin II Type 2 Receptor

Alternate Names

AGTR2, AT2, AT2R, MRX88

Entrez Gene IDs

186 (Human); 11609 (Mouse); 24182 (Rat)

Gene Symbol

AGTR2

UniProt

P50052

Additional AGTR-2 Products

Product Documents for Human AGTR-2 PE-conjugated Antibody

Product Datasheets

Download Product Datasheets

COA

SDS

Download SDS

Product Specific Notices for Human AGTR-2 PE-conjugated Antibody

For research use only

Citations
Reviews

Spectra Viewer
Flow Cytometry

Human AGTR-2 PE-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB3659P

Key Product Details

Species Reactivity

Applications

Label

Antibody Source

View all AGTR-2 Antibodies »

Product Specifications

Immunogen

Specificity

Clonality

Host

Isotype

Scientific Data Images for Human AGTR-2 PE-conjugated Antibody

Detection of AGTR-2 in NS0 Mouse Cell Line Transfected with AGTR-2 by Flow Cytometry.