Skip to main content

Human APP/Protease Nexin II (Research Grade Solanezumab Biosimilar) Antibody

R&D Systems, part of Bio-Techne | Catalog # MAB9919

Recombinant Monoclonal Antibody For Research Use Only
R&D Systems, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
Loading...
MAB9919-100
MAB9919-SP

Key Product Details

Species Reactivity

Human

Applications

CyTOF-ready, Flow Cytometry

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Human IgG1 Clone # Hu13

Product Specifications

Immunogen

Human APP/Protease Nexin II

Specificity

Detects Human APP/Protease Nexin II based on Solanezumab therapeutic antibody. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Solanezumab. This product is for research use only.

Clonality

Monoclonal

Host

Human

Isotype

IgG1

Endotoxin Level

<0.10 EU per 1 μg of the antibody by the LAL method.

Scientific Data Images

Detection of APP/Protease Nexin II antibody in Human PBMC antibody by Flow Cytometry.

Detection of APP/Protease Nexin II in Human PBMC by Flow Cytometry.

Human PBMC were stained with (A) Human Anti-Human APP/Protease Nexin II (Solanezumab Biosimilar) Monoclonal Antibody (Catalog # MAB9919) or (B) Human IgG isotype control antibody followed by anti-Human IgG APC-conjugated Secondary Antibody (Catalog # F0135) and Mouse anti-Human CD14 PE-conjugated Monoclonal Antibody (Catalog # FAB3832P). View our protocol for Staining Membrane-associated Proteins.

Applications

Application
Recommended Usage

CyTOF-ready

Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.

Flow Cytometry

0.25 µg/106 cells
Sample: Human PBMC
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from cell culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Reconstitution Buffer Available:
Size / Price
Qty
Loading...

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: APP

Solanezumab is a biosimilar directed against the extracellular domain of APP/Protease Nexin II. This product can be used in flow cytometry or various assay formats to measure APP/Protease Nexin II.

Long Name

Amyloid Precursor Protein

Alternate Names

Amyloid beta, beta Amyloid, Protease Nexin II

Entrez Gene IDs

351 (Human); 11820 (Mouse)

Gene Symbol

APP

Additional APP Products

Product Documents

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices

For research use only

Loading...
Loading...
Loading...
Loading...
Loading...
Loading...