Human Caspr2 Biotinylated Antibody

R&D Systems, part of Bio-Techne | Catalog # BAF5145

R&D Systems, part of Bio-Techne
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AF5145
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Biotin

Antibody Source

Polyclonal Sheep IgG

View all Caspr2 Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human Caspr2 isoform 1
Pro29-Ala1262
Accession # Q9UHC6

Specificity

Detects human Caspr2 in Western blots.

Clonality

Polyclonal

Host

Sheep

Isotype

IgG

Applications for Human Caspr2 Biotinylated Antibody

Application
Recommended Usage

Western Blot

0.1 µg/mL
Sample: Recombinant Human Caspr2
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Reconstitution Buffer Available:
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Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Caspr2

Contactin-associated protein 2 (Caspr2) is a neuronal membrane protein and member of the neurexin family. Caspr2 is the mammalian homolog of Drosophila Neurexin IV. Caspr2 is believed to be involved in the local differentiation of the axon into distinct functional subdomains. Studies have shown that Caspr2 is essential for clustering of Shaker-type K+ channels in the juxtaparanodes of Ranvier. This effect is dependent on the association of Caspr2 with TAG-1, a glycosyl-phosphatidyl-inositol-anchored cell adhesion molecule. Mutations in Caspr2 are associated with the development of autism and related disorders.

Long Name

Contactin Associated Protein-like 2

Alternate Names

CDFE, CNTNAP2, NRXN4

Entrez Gene IDs

26047 (Human); 66797 (Mouse)

Gene Symbol

CNTNAP2

UniProt

Q9UHC6

Additional Caspr2 Products

Product Documents for Human Caspr2 Biotinylated Antibody

Product Datasheets

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human Caspr2 Biotinylated Antibody

For research use only

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