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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Flow Cytometry

Cited:

Flow Cytometry

Label

Phycoerythrin (Excitation = 488 nm, Emission = 565-605 nm)

Antibody Source

Monoclonal Mouse IgG1 Clone # ICRF 3.9

Product Specifications

Immunogen

Rheumatoid synovial fluid cells and human monocyte-derived fibronectin

Specificity

Detects human CD11c in flow cytometry.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Human CD11c PE-conjugated Antibody

Detection of CD11c antibody in Human PBMCs antibody by Flow Cytometry.

Detection of CD11c in Human PBMCs by Flow Cytometry.

Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human CD14 APC-conjugated Monoclonal Antibody (Catalog # FAB3832A) and either (A) Mouse Anti-Human CD11c PE-conjugated Monoclonal Antibody (Catalog # FAB1777P) or (B) Mouse IgG1Phycoerythrin Isotype Control (Catalog # IC002P). View our protocol for Staining Membrane-associated Proteins.

Applications for Human CD11c PE-conjugated Antibody

Application
Recommended Usage

Flow Cytometry

10 µL/106 cells
Sample: Human peripheral blood mononuclear cells (PBMCs)

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: CD11c

Integrin alphaX, also known as CD11c, heterodimerizes with Integrin beta2, also known as CD18. The CD11c/CD18 complex binds fibrinogen and has been reported to be a receptor for iC3b (1‑3) .

References

  1. Hogg, N. et al. (1986) Eur. J. Immunol. 16(3):240.
  2. Knapp, W.B. et al. eds. (1989) Leukocyte Typing IV: White Cell Differentiation Antigens, Oxford University Press, New York.
  3. Stacker, S.A. and T.A. Springer, J. Immunol. (1991) 146(2):648.

Alternate Names

CD11c, Integrin alpha X, ITGAX, p150,95 alpha

Entrez Gene IDs

3687 (Human); 16411 (Mouse); 64350 (Rat)

Gene Symbol

ITGAX

Additional CD11c Products

Product Documents for Human CD11c PE-conjugated Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human CD11c PE-conjugated Antibody

For research use only

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