Human CD31/PECAM‑1 Biotinylated Antibody
R&D Systems, part of Bio-Techne | Catalog # BAF806
Key Product Details
Species Reactivity
Validated:
Human
Cited:
Transgenic Mouse
Applications
Validated:
Western Blot
Cited:
Immunohistochemistry
Label
Biotin
Antibody Source
Polyclonal Sheep IgG
Product Specifications
Immunogen
Chinese hamster ovary cell line CHO-derived recombinant human CD31
Extracellular domain
Extracellular domain
Specificity
Detects human CD31 in Western blots. In this format, less than 1% cross-reactivity with recombinant human (rh) ALCAM, rhEpCAM, rhICAM‑1, and rhVCAM‑1 is observed.
Clonality
Polyclonal
Host
Sheep
Isotype
IgG
Applications for Human CD31/PECAM‑1 Biotinylated Antibody
Application
Recommended Usage
Western Blot
0.1 µg/mL
Sample: Recombinant Human CD31/PECAM-1 (Catalog # ADP6)
Sample: Recombinant Human CD31/PECAM-1 (Catalog # ADP6)
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: CD31/PECAM-1
The CD31 adhesion molecule, also known as PECAM-1, is expressed in large amounts on endothelial cells at intercellular junctions and on T cell subsets, and to a lesser extent on platelets and most other leukocytes such as monocytes and neutrophils. CD31 binds to itself homotypically, and also to the leukocyte integrin alphav beta3 heterotypically. CD31 is required for the transendothelial migration of leukocytes through intercellular junctions of vascular endothelial cells. CD31 has been found in human plasma, and the presence of this circulating isoform is suggested to modulate the transendothelial migration of leukocytes.
Long Name
Platelet Endothelial Cell Adhesion Molecule 1
Alternate Names
CD31, EndoCAM, PECA1, PECAM-1, PECAM1
Gene Symbol
PECAM1
Additional CD31/PECAM-1 Products
Product Documents for Human CD31/PECAM‑1 Biotinylated Antibody
Product Specific Notices for Human CD31/PECAM‑1 Biotinylated Antibody
For research use only
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